Results 171 to 180 of about 2,830,265 (289)

Legal Beagle Blog (June 2008) [PDF]

open access: yes, 2008
Roger Williams University School of Law Library
core   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu   +6 more
wiley   +1 more source

CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples. [PDF]

open access: yesMol Cell
Cao Z   +14 more
europepmc   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

open access: yesAdvanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li   +25 more
wiley   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

open access: yesAdvanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu   +4 more
wiley   +1 more source

Correction: Evidence for Digital Health Tools Designed to Support the Triage of Musculoskeletal Conditions in Primary, Urgent, and Emergency Care Settings: Scoping Review.

open access: yesJ Med Internet Res
Truong LK   +12 more
europepmc   +1 more source

Genome sequence of the yeast <i>Candida sake</i> UCD2293, isolated from soil in Ireland. [PDF]

open access: yesMicrobiol Resour Announc
Osborne M   +13 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy