Results 211 to 220 of about 31,901,677 (295)

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Prioritizing neuroactive ligands using motif-guided virtual discovery and zebrafish profiling. [PDF]

NPJ Drug Discov
Ginsparg AB, Martinez JA, Patel I, Buton A, Lee LT, Sarwar R, Moretti R, Puig S, Thyme SB.   +8 more
europepmc   +1 more source

High‐Throughput Screening and Interpretable Machine Learning for Rational Design of Bimetallic Catalysts for Methane Activation

Advanced Science, EarlyView.
ABSTRACT Methane's efficient catalytic removal is vital for sustainable development. Bimetallic catalysts, though promising for methane activation, pose a design challenge due to their complex compositional space. This work introduces an integrated framework that combines high‐throughput density functional theory (DFT) and interpretable machine ...
Mingzhang Pan, Tian Zhang, Jiawei Dong, Yubao Xie, Kaifeng Zhong, Wei Guan, Haiqiao Wei, Changcheng Fu, Yaqiong Su   +8 more
wiley   +1 more source

The fitness landscape of a form II rubisco in a photosynthetic bacterium guides engineering of oxygen tolerance. [PDF]

Sci Adv
Hoffmann UA, Knave AF, Schuppe AZ, Capó-Bauçà S, Aguiló Nicolau P, Schriever K, Karlsson A, Russo M, Sporre E, Matsuda M, Miao R, Hasunuma T, Galmés J, Syrén PO, Hudson EP.   +14 more
europepmc   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Humoral pregnancy analyses reveal strategies for fetal protection and aberrancy in miscarriage. [PDF]

Cell Rep Med
Sie BM, Leng Y, Nziza N, Mitchell MM, Webb NE, Lee Y, Mumford SL, Schisterman EF, Larman HB, Julg B, Alter G, Elledge SJ.   +11 more
europepmc   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

Corrigendum to "Circular RNA: From non-coding regulators to functional protein encoders" [Pharmaceut. Sci. Adv. 3 (2025), 100085]. [PDF]

Pharm Sci Adv
Zhang X, Wu H, Hong X, Xiao Y, Zeng X.
europepmc   +1 more source

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

<i>In vivo</i> selection of anti-glioblastoma DNA aptamer-drug conjugates in an orthotopic patient-derived xenograft model. [PDF]

NAR Cancer
Doherty CD, Jain S, Ott LL, Bakken KK, Wilbanks BA, Burgenske DM, Pearson KS, Griffith JI, Tian Z, Meridew JA, Yerneni SS, Elmquist WF, Sarkaria JN, Maher Iii LJ.   +13 more
europepmc   +1 more source