Results 271 to 280 of about 2,872,164 (338)

Single-cell RNA-seq data normalization: A benchmarking study. [PDF]

PLoS One
Ge Q, Sheng Y, Lu J, Yang Y, Pan M.
europepmc   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Solid-phase synthesis of polyunsaturated fatty acids facilitates precise structural investigation on FFAR1/4 agonist activities and the inhibition of neutrophil pseudopod formation. [PDF]

RSC Adv
Shi Y, Saito Y, Hotta M, Akita M, Uwamizu A, Aoki J, Kunisawa J, Sando S.   +7 more
europepmc   +1 more source

Legal Beagle Blog (October 2009) [PDF]

, 2009
Roger Williams University School of Law Library
core   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Protocol for discovering genetic variants associated with ATAC-seq footprint-inferred transcription factor binding. [PDF]

STAR Protoc
Dudek MF, Wenz BM, Voight BF, Almasy L, Grant SFA.   +4 more
europepmc   +1 more source

Functional Mapping of Epigenomic Regulators Uncovers Coordinated Tumor Suppression by the HBO1 and MLL1 Complexes. [PDF]

Cancer Discov
Tang YJ, Xu H, Hughes NW, Ruiz P, Kim SH, Shuldiner EG, Lopez SS, Hebert JD, Karmakar S, Andrejka L, Dolcen DN, Boross G, Chu P, Kunder CA, Detrick C, Pierce SE, Ashkin EL, Greenleaf WJ, Voss AK, Thomas T, van de Rijn M, Petrov DA, Winslow MM.   +22 more
europepmc   +1 more source

Legal Beagle Blog (March 2010) [PDF]

, 2010
Roger Williams University School of Law Library
core   +4 more sources

A Rapid, High-Throughput Method for the Construction of Mutagenesis Libraries. [PDF]

Biomolecules
Lu Y, Meng S, Guan X, He P, Zhao D.
europepmc   +1 more source