Results 81 to 90 of about 1,021,934 (247)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
1909 School of Marine Engineering (poster) [PDF]
, 2014 A poster image of showing the the School of Marine Engineering at the Naval Academy in Annapolis in 1909, and the USS Connecticut, flagship of the Great White ...
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Department of Metallurgical and Materials Engineering newsletter Summer 2021
, 2021 "A Newsletter for Friends & Supporters of the Colorado School of Mines' George S.
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FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Department of Petroleum Engineering newsletter 1997
, 1997 "Newsletter of the Petroleum Engineering Department Colorado School of ...
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Department of Metallurgical and Materials Engineering newsletter Spring 2022
, 2022 "A Newsletter for Friends & Supporters of the Colorado School of Mines' George S.
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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Department of Metallurgical and Materials Engineering newsletter Summer 2020
, 2020 "A Newsletter for Friends & Supporters of the Colorado School of Mines' George S.
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Department of Metallurgical and Materials Engineering newsletter Spring 2023
, 2023 "A Newsletter for Friends & Supporters of the Colorado School of Mines' George S.
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Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source