Results 81 to 90 of about 11,045,215 (246)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Re-forming leadership at a whole-school level: teacher leaders and their principal invoking reaction within and beynd their school

open access: yes, 2014
Leadership at a whole-school level is the key to sustainable school improvement. Research across Australia in schools of several education systems has revealed the importance of parallel leadership if there is to be collective responsibility for ...
Conway, Joan M.
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Advisory Panel on School Principal Training Meeting, 22 October 2002

open access: yes, 2002
Meeting documents of the Advisory Panel on School Principal Training including: (1.) Notice (2.) Minutes of the meeting held on 1 August 2002 (3.) Objectives of the Advisory panel (4.) Principle training module (5.)Action ...
Forbes, Andre
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Engineering School

open access: yes, 1955
Contents include "Historical Sketch of the Naval Postgraduate School"; "The Engineering ...

core   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Entrepreneurial Management Practices of School Principals to Enhance Financing Standard Quality in Primary Education

open access: yesJP (Jurnal Pendidikan)
This study examines the implementation of entrepreneurial management by primary school principals in addressing the limitations of School Operational Assistance (BOS) funding in Bireuen District, Aceh, Indonesia.
Feranida Feranida   +2 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Naval Postgraduate School Foundation Homepage

open access: yes, 2014
Screenshot of the Naval Postgraduate School Foundation website.Homepage of the Naval Postgraduate School ...
Naval Postgraduate School Foundation
core   +2 more sources

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