Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
The influence of nutritional status, the home environment, and schooling on behavioral outcomes of hyperactivity and inattention among grade-school children in rural Nepal. [PDF]
Zavala E +8 more
europepmc +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
The effects of parental education on male mortality: evidence from the first wave of compulsory schooling laws. [PDF]
Noghanibehambari H, Amin V, Fletcher J.
europepmc +1 more source
A Structural Analysis of the Correlated Random Coefficient Wage Regression Model [PDF]
We estimate a finite mixture dynamic programming model of schooling decisions in which the log wage regression function is set in a random coefficient framework.
Christian Belzil, Jörgen Hansen
core
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Biological aging and lifespan in men and women using a Mendelian randomization study. [PDF]
Schooling CM, Li S, Jiesisibieke ZL.
europepmc +1 more source
Migration Enclaves, Schooling Choices and Social Mobility [PDF]
This paper investigates the presence of a network externality which might explain the persistence of low schooling achievements among internal migrants.
Piacentini, Mario
core +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
School Attendance Pre- and Post-Pandemic in Adolescents with Chronic Pain. [PDF]
Berry JR +3 more
europepmc +1 more source

