Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
More Schooling, More Children [PDF]
We study the relationship between education and fertility, exploiting compulsory schooling reforms in Europe as source of exogenous variation in education.
Schneeweis, Nicole +2 more
core
School Entry Deferral: Effects of Age and Schooling on Children's Longitudinal Executive Function Development and Parent-Reported Socio-Emotional and Regulatory Outcomes. [PDF]
Simpson HG, Chevalier N, Booth JN.
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
The fading productivity of schooling in East Asia. [PDF]
We estimate changes in the productivity of schooling for six East Asian countries. Our productivity measure is based on changes in the relative price of schooling.
Wößmann, Ludger, Gundlach, Erich
core
The pressures of functional differentiation: education, homework, and schooled families. [PDF]
Vanderstraeten R, Labraña J, Koch T.
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
The Determinants of Schooling in Egypt: The Role of Gender and Rural-Urban Residence [PDF]
This paper examines the role of gender and rural-urban residence, and the interaction between them in influencing schooling outcomes, using household level cross-section data from Egypt.
Dancer, Diane M., Rammohan, Anu
core
Gender Gaps in School Grades: Resistance Behavior and Class Compositions in England, Germany, The Netherlands, and Sweden. [PDF]
Raabe IJ, Steinmann I.
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source

