Results 131 to 140 of about 92,204 (266)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Multi-method validation of the new computerized test of fluid intelligence MatriKS. [PDF]

open access: yesBehav Res Methods
de Chiusole D   +12 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Portraits of Rural Education: the schooling of residents of the Bom Lugar I Settlement, Upanema – RN

open access: yesRevista Brasileira de Educação do Campo
This study's central theme is the schooling of residents of the Bom Lugar I Settlement, Upanema – RN. It started with the following research problem: what is the education level of the residents of Settlement Bom Lugar I, Upanema-RN?
Ana Cleide da Silva de Oliveira   +2 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Numeracy, literacy, and formal education as mechanisms of inequities in late-life cognitive performance between Indigenous-speaking and non-Indigenous-speaking older Mexican adults. [PDF]

open access: yesAlzheimers Dement
Gutierrez S   +11 more
europepmc   +1 more source

À propos du système éducatif nigérien

open access: yesRevue Internationale d’Éducation de Sèvres, 2021
Abdoulaye Boubakar Diallo
doaj   +1 more source

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