Results 51 to 60 of about 4,284,500 (337)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The objectives and instructional design of undergraduate endodontic program: multicenter cross-sectional study in Saudi Arabia

BMC Medical Education, 2022
Background Identify the objectives and the instructional design of undergraduate endodontics in dental schools in Saudi Arabia. Methods The online questionnaire was developed from an original survey conducted in the United Kingdom.
Fahda N. Algahtani, Reem M. Barakat, Rahaf A. Almohareb, Lujain Alqarni, Alanoud Alqabbani, Ebtisam Almadi   +5 more
doaj   +1 more source

It's About Time: Learning Time and Educational Opportunity in California High Schools [PDF]

, 2014
A new study by the UCLA Institute for Democracy, Education and Access (IDEA) found that teachers in high-poverty schools are more likely than their peers in low-poverty schools to report more time lost for academic instruction due to poor access to ...
John Rogers, Nicole Mirra
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Disinfection Trends of Dental X-ray Machines in North American Dental Schools

Journal of Orofacial Sciences, 2020
Introduction: This study evaluates the trends in the disinfection of the dental X-ray machines in North American dental schools. The methods of disinfection were compared to the Centers for Disease Control (CDC) guidelines.
Mel Mupparapu, Angela Denise Lo
doaj   +1 more source

Gender Trends in Dental Leadership and Academics: A Twenty-Two-Year Observation [PDF]

, 2010
The purpose of this study was to examine gender disparities in dental leadership and academics in the United States. Nine journals that represent the dental specialties and high published impact factors were selected to analyze the percentage of female ...
Koerber, Anne, Kongkiatkamon, Suchada, Lee, Damian J., Prasad, Soni, Ross, Sasha, Sukotjo, Cortino, Yuan, Judy Chia-Chun   +6 more
core   +1 more source

Effectiveness and reach of a directed-population approach to improving dental health and reducing inequalities: a cross sectional study [PDF]

, 2013
Background Childsmile School adopts a directed-population approach to target fluoride varnish applications to 20% of the primary one (P1) population in priority schools selected on the basis of the proportion of enrolled children considered to be at ...
Andrea Sherriff, BA Burt, BR Kirkwood, D Locker, D Sagheri, G Rose, J Emberson, KL Frohlich, KM Milsom, L McLaren, LMD Macpherson, LMD Macpherson, Lorna Macpherson, Lynn Brewster, M Tickle, M Tickle, MZ Morgan, R Beaglehole, R Haynes, RG Watt, S Government, The Marmot Review   +21 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

An Update on Practice Management Instruction in U.S. Dental Schools

Dental Hypotheses, 2012
Over the last twenty-seven years, the evaluation of practice management in dental schools has been documented by three studies. In twenty-seven years the teaching of practice management has been influenced by changes in the definition of practice manage ...
Brian M. Lange, David G. Dunning, Wenyu Qu   +2 more
doaj   +3 more sources

CURRENT TRENDS IN DENTAL EDUCATION

Pakistan Armed Forces Medical Journal, 2021
The dental profession is an important segment of human health care services all over the world. Dental schools in Europe and United States have evolved their curriculum to keep abreast with advances in dentistry; like connective tissue biophysics and ...
Ayesha Ghassan, Irfan Shukr, Naushaba Sadiq, Rabia Ahsan   +3 more
doaj   +1 more source