Results 111 to 120 of about 8,655,714 (345)

Impact of the COVID-19 pandemic on medical education: Medical students’ knowledge, attitudes, and practices regarding electronic learning

PLoS ONE, 2020
The Coronavirus Disease 2019 (COVID-19) pandemic has caused an unprecedented disruption in medical education and healthcare systems worldwide. The disease can cause life-threatening conditions and it presents challenges for medical education, as ...
A. Alsoufi, Ali Alsuyihili, A. Msherghi, A. Elhadi, Hana Atiyah, Aimen Ashini, Arwa Ashwieb, Mohamed Ghula, Hayat Ben Hasan, Salsabil Abudabuos, Hind Alameen, Taqwa Abokhdhir, Mohamed Anaiba, T. Nagib, A. Shuwayyah, Rema Benothman, Ghalea Arrefae, Abdulwajid Alkhwayildi, Abdulmueti Alhadi, A. Zaid, M. Elhadi   +20 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Plasma biomarkers are associated with agitation and regional brain atrophy in Alzheimer’s disease

Scientific Reports, 2017
This study investigated the relationships among plasma biomarkers, regional brain atrophy, and clinical symptoms in patients with Alzheimer’s disease (AD; n = 177), mild cognitive impairment (MCI; N = 60) and controls (n = 108).
Jung-Lung Hsu, Wei-Ju Lee, Yi-Chu Liao, Jiing-Feng Lirng, Shuu-Jiun Wang, Jong-Ling Fuh   +5 more
doaj   +1 more source

Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review

Systematic Reviews, 2018
Background Alcohol and substance use results in significant human and economic cost globally and is associated with economic costs of £21 billion and £15billion within the UK, respectively, and trends for use are not improving.
Tom P. Thompson, Adrian H. Taylor, Amanda Wanner, Kerryn Husk, Yinghui Wei, Siobhan Creanor, Rebecca Kandiyali, Jo Neale, Julia Sinclair, Mona Nasser, Gary Wallace   +10 more
doaj   +1 more source

Librarians use of Web 2.0 in UK Medical Schools: Outcomes of a national survey [PDF]

, 2010
Using the results of an Email survey, this paper reviews the use of Web 2.0 technologies by librarians working in UK Medical Schools. Web 2.0 has been hailed as an innovation for facilitation of two way communication on the net, and it is, therefore ...
Grant, V, Kuhn, I, Pacheco, J
core   +1 more source

The experiences of medical students and junior doctors with dyslexia: a survey study [PDF]

, 2020
Little research exists concerning dyslexia in medical education. A qualitative study highlighted issues such as bullying and a lack of support. This project aimed to quantify those findings.
Anderson, John L, Shaw, Sebastian C K
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Spirituality and health in the curricula of medical schools in Brazil [PDF]

, 2012
Background: According to recent surveys, 59% of British medical schools and 90% of US medical schools have courses or content on spirituality and health (S/H).
Espinha, Daniele Corcioli Mendes, Koenig, Harold G., Leite, Jose Roberto, Lucchetti, Alessandra Lamas Granero, Lucchetti, Giancarlo, Oliveira, Leandro Romani de   +5 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A survey study of evidence-based medicine training in US and Canadian medical schools.

Journal of the Medical Library Association, 2014
PURPOSE The authors conducted a survey examining (1) the current state of evidence-based medicine (EBM) curricula in US and Canadian medical schools and corresponding learning objectives, (2) medical educators' and librarians' participation in EBM ...
M. Blanco, C. Capello, J. Dorsch, G. Perry, M. Zanetti   +4 more
semanticscholar   +1 more source