Results 91 to 100 of about 112,215 (282)
Biocatalytic Regioselective C‐Formylation of Resorcinol Derivatives
Angewandte Chemie, EarlyView.An acyltransferase from Chromobacterium sphagni (CsATase) was identified that catalyzes the regioselective formylation of resorcinol substrates. The formylation of substituted resorcinol derivatives yielded mono‐formylated products with up to 99% conversion and up to 74% isolated yield.
Lilla Gal +6 more
wiley +2 more sources
Learned Conformational Space and Pharmacophore Into Molecular Foundational Model
Advanced Science, EarlyView.The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang +8 more
wiley +1 more source
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source
A Nonlinear Schrödinger Equation Resonating at an Essential Spectrum
Advances in Mathematical Physics, 2016 We consider the nonlinear Schrödinger equation -Δu+f(u)=V(x)u in RN. The potential function V satisfies that the essential spectrum of the Schrödinger operator -Δ-V is [0,+∞) and this Schrödinger operator has infinitely many negative eigenvalues ...
Shaowei Chen, Haijun Zhou
doaj +1 more source
Gallium Nitride Semiconductor Resonant Tunneling Transistor
Advanced Science, EarlyView.Three‐terminal GaN semiconductor resonant tunneling transistors (RTTs), which comprise an double‐barrier AlN/GaN/AlN resonant tunneling diode integrated with a GaN high‐electron‐mobility transistor (HEMT) through epitaxial growth in series and parallel configuraions, respectively.
Fang Liu +15 more
wiley +1 more source
Computational Simulations; Abundant Optical Wave Solutions Atangana Conformable Fractional Nonlinear Schrödinger Equation [PDF]
, 2022 Mostafa M. A. Khater +2 more
openalex +1 more source
Advanced Science, EarlyView.The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
Kaonic deuterium and low-energy antikaon-nucleon interaction
, 2017 A new evaluation of the $1s$ level shift and width of kaonic deuterium is presented based on an accurate $\bar{K}NN$ three-body calculation, using as input a realistic antikaon-nucleon interaction constrained by the SIDDHARTA kaonic hydrogen data.
Horiuchi, Wataru +2 more
core +1 more source
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
Advanced Science, EarlyView.His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source