Results 41 to 50 of about 112,215 (282)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Energy decay rate of multidimensional inhomogeneous Landau–Lifshitz–Gilbert equation and Schrödinger map equation on the sphere

open access: yesAdvances in Difference Equations, 2018
We consider the multidimensional dimensional inhomogeneous Landau–Lifshitz–Gilbert (ILLG) equation and its degenerate case, the Schrödinger map equation.
Penghong Zhong, Chao Zhang, Fengong Wu
doaj   +1 more source

Some Spectral Properties of Schrödinger Operators on Semi Axis

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
The main aim of this work is to investigate some spectral properties of Schrödinger operators on semi axis. We first present the Schrödinger equation with a piecewise continuous potential function q so that the problem differs from the classical ...
İbrahim Erdal
doaj   +1 more source

Newton-Cartan Gravity and Torsion [PDF]

open access: yes, 2017
We compare the gauging of the Bargmann algebra, for the case of arbitrary torsion, with the result that one obtains from a null-reduction of General Relativity.
Cheng-Yan Mou (4269523)   +7 more
core   +7 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Solving a nonlinear fractional Schrödinger equation using cubic B-splines

open access: yesAdvances in Difference Equations, 2020
We study the inhomogeneous nonlinear time-fractional Schrödinger equation for linear potential, where the order of fractional time derivative parameter α varies between 0 < α < 1 $0 < \alpha < 1$ .
M. Erfanian   +3 more
doaj   +1 more source

Infinite order symmetries for two-dimensional separable Schrödinger equations [PDF]

open access: yes, 2004
Consider a non-relativistic Hamiltonian operator H in 2 dimensions consisting of a kinetic energy term plus a potential. We show that if the associated Schrödinger eigenvalue equation admits an orthogonal separation of variables, there is a calculus to ...
Kalnins, Ernie G.   +2 more
core  

Weakly nonparaxial effects on the propagation of (1+1)D spatial solitons in inhomogeneous Kerr media [PDF]

open access: yes, 2005
The widely-used approach to study the beam propagation in Kerr media is based on the slowly varying envelope approximation (SVEA) which is also known as the paraxial approximation.
Groesen, E. van   +2 more
core   +3 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Strong confinement limit for the nonlinear Schrödinger equation constrained on a curve [PDF]

open access: yes, 2016
International audienceThis paper is devoted to the cubic nonlinear Schrödinger equation in a two dimensional waveguide with shrinking cross section.
Méhats, Florian, Raymond, Nicolas
core   +4 more sources

Home - About - Disclaimer - Privacy