Results 131 to 140 of about 39,475 (232)
Movement Disorders Clinical Practice, EarlyView.Abstract Background LRRK2‐Parkinson's disease (LRRK2‐PD) is biologically heterogeneous with approximately 30% lacking aggregated alpha synuclein (αSyn) in cerebrospinal fluid by seed amplification assay (SAA). Prior work has suggested slower progression in LRRK2‐PD compared to sporadic PD (sPD).
Lucy A. Morse +224 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker +30 more
wiley +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano +4 more
wiley +1 more source
Unveiling New Perspectives on the Hirota–Maccari System With Multiplicative White Noise
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT In this study, we delve into the stochastic Hirota–Maccari system, which is subjected to multiplicative noise according to the Itô sense. The stochastic Hirota–Maccari system is significant for its ability to accurately model how stochastic affects nonlinear wave propagation, providing valuable insights into complex systems like fluid dynamics
Mohamed E. M. Alngar +3 more
wiley +1 more source
How to Renormalize the Schrodinger Equation
, 1997 Lectures given at the VIII Jorge Andre Swieca Summer School (Brazil, 1997). One file producing 46 pages; LaTeX using World Scientific's sprocl.sty (not essential)
openaire +2 more sources
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT Nonlinear differential equations play a fundamental role in modeling complex physical phenomena across solid‐state physics, hydrodynamics, plasma physics, nonlinear optics, and biological systems. This study focuses on the Shynaray II‐A equation, a relatively less‐explored parametric nonlinear partial differential equation that describes ...
Aamir Farooq +4 more
wiley +1 more source
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT The main results of this paper are the global existence and long time behavior of solutions of a fractional wave equation with a nonlocal nonlinearity. The techniques in this work rely on norm estimates of the solutions of εutt+ut+(−Δ)βu=0,u(0,x)=φ(x),ut(0,x)=ψ(x),$$ \varepsilon {u}_{tt}+{u}_t+{\left(-\Delta \right)}^{\beta }u=0,\kern1em u ...
Ibrahim Ahmad Suleman, Mokhtar Kirane
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Current Insight into Human Ornithine Aminotransferase: A Review
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani +2 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake +6 more
wiley +1 more source
Schrodinger Equation cannot Describe Transition Processes
, 2001 18 pages with 1 ...
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