Results 51 to 60 of about 25,004 (307)

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Steady-state solutions for Schrodinger equations in photonic lattice

Electronic Journal of Differential Equations, 2018
In this article, we study a nonlinear Schrodinger equation arising in optics. Firstly we prove the existence of multiple solutions of this equation. Secondly, we consider a nonlinear Schrodinger system which is intimately related to the Schrodinger ...
Wen-Long Li
doaj  

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Novel soliton solutions and phase plane analysis in nonlinear Schrödinger equations with logarithmic nonlinearities

Scientific Reports
This paper investigates a generalized form of the nonlinear Schrödinger equation characterized by a logarithmic nonlinearity. The nonlinear Schrödinger equation, a fundamental equation in nonlinear wave theory, is applied across various physical systems ...
Du’a Al-zaleq, Lewa’ Alzaleq
doaj   +1 more source

Asymptotic behavior of dark multi-solitons to the intermediate nonlinear Schrödinger equation

Partial Differential Equations in Applied Mathematics
The intermediate nonlinear Schrödinger equation (abbreviated to (INS)) is a model equation for envelope waves in a deep stratified fluid and can be thought of as a generalization of the defocusing nonlinear Schrödinger equation. Furthermore, it possesses
Takafumi Akahori
doaj   +1 more source

Exact Multisoliton Solutions of General Nonlinear Schrödinger Equation with Derivative

The Scientific World Journal, 2014
Multisoliton solutions are derived for a general nonlinear Schrödinger equation with derivative by using Hirota’s approach. The dynamics of one-soliton solution and two-soliton interactions are also illustrated.
Qi Li, Qiu-yuan Duan, Jian-bing Zhang
doaj   +1 more source

Transcendental equation for the Schrödinger equation [PDF]

Mathematics of Computation, 1960
side of eq. (4). The hypergeometric function appearing in eq. (4) can be computed as described above but convergence is slow for values of x close to unity, and in this case it may be desirable to compute the functions differently [4]. A subroutine [5] has been written for the IBM 704 to calculate the toroidal harmonics using the methods described here.
openaire   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Integration of the Loaded Negative Order Nonlinear Schrodinger Equation in the Class of Periodic Functions

Известия Иркутского государственного университета: Серия "Математика"
In this paper, we consider the loaded negative order nonlinear Schrodinger equation (NSE) in the class of periodic functions. It is shown that the loaded negative order nonlinear Schrodinger equation can be integrated by the inverse spectral problem ...
M. M. Khasanov, I. D. Rakhimov, D. B. Azimov   +2 more
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source