Results 61 to 70 of about 46,328 (199)

Lung Biopsies in Patients Referred for Allogeneic Hematopoietic Cell Transplantation: Diagnostic Accuracy, Diagnostic Yield, and Clinical Utility

Transplant Infectious Disease, EarlyView.
Among patients referred for allogeneic hematopoietic cell transplantation with pulmonary opacities, lung biopsy provided a diagnosis in 72% of procedures and altered management in 51%. Despite a 7% major complication rate, lung biopsy frequently clarified noninfectious etiologies when bronchoscopy was inconclusive.
Sergio Rodriguez‐Rodriguez, Ayman Sayyed, Swe Mar Linn, Caden Chiarello, Mats Remberger, Igor Novitzky‐Basso, Patrik Rogalla, Shahid Husain, Jonas Mattsson   +8 more
wiley   +1 more source

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]

, 2016
BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas, Chmielowski, Bartosz, Crompton, Joseph G, Dry, Sarah, Eilber, Fritz C, Federman, Noah, Jensen, Sarah, Li, Yunfeng, Nelson, Scott, Shurell, Elizabeth, Singh, Arun S, Tumeh, Paul   +11 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

The molecular pathogenesis of schwannomatosis, a paradigm for the co-involvement of multiple tumour suppressor genes in tumorigenesis [PDF]

, 2016
Schwannomatosis is characterized by the predisposition to develop multiple schwannomas and, less commonly, meningiomas. Despite the clinical overlap with neurofibromatosis type 2 (NF2), schwannomatosis is not caused by germline NF2 gene mutations ...
Cooper, David Neil, Farschtschi, Said, Kehrer-Sawatzki, Hildegard, Mautner, Victor-Felix   +3 more
core   +1 more source

Adjunctive Hyperbaric Oxygen Therapy or Intratympanic Steroids in Sudden Sensorineural Hearing Loss?

The Laryngoscope, Volume 136, Issue 6, Page 2708-2718, June 2026.
Sudden sensorineural hearing loss is traditionally treated with steroids, either orally and/or via intratympanic injections, and hyperbaric oxygen treatment (HBOT) has resurged in popularity as an adjunctive therapy. The study has not found any additional treatment benefit with adjunctive concurrent HBOT; however, HBOT might be of value to patients ...
Jennifer L. Spiegel, Michael J. De Biasio, Gianluca Sampieri, Omer J. Ungar, Munir D. Bajin, Vincent Y. W. Lin, Joseph M. Chen, Chris Idestrup, Jordan Tarshis, Trung N. Le   +9 more
wiley   +1 more source

Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells. [PDF]

, 2013
Loss of the Merlin tumour suppressor causes abnormal de-differentiation and proliferation of Schwann cells and formation of schwannoma tumours in patients with neurofibromatosis type 2.
Doddrell, RDS, Dun, X-P, Feltri, ML, Hanemann, CO, Parkinson, DB, Shivane, A, Sock, E, Wegner, M, Wrabetz, L   +8 more
core   +2 more sources

TANC1::HTRA1 fusion in schwannomas

Brain Pathology, EarlyView.
Ilay Caliskan, Kanish Mirchia, Walter Patrick Devine, Melike Pekmezci   +3 more
wiley   +1 more source

Efficacy of a Quantitative Intra‐Operative Facial Nerve Continuous Monitoring System for Functional Preservation Following Intratemporal Facial Nerve Schwannoma Resection

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
We investigated the role of a continuous, quantitative intraoperative monitoring system in surgeries for facial nerve schwannomas, a rare tumor associated with a high risk of facial nerve dysfunction. By continuously stimulating the facial nerve and recording electromyographic responses in real time, the system enabled surgeons to detect subtle or ...
Makoto Hosoya, Marie N. Shimanuki, Masafumi Ueno, Satoshi Suda, Takeshi Wakabayashi, Takanori Nishiyama, Hiroyuki Ozawa, Naoki Oishi   +7 more
wiley   +1 more source

Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature? [PDF]

, 2010
Schwannomas, also known as neurilemmomas, are uncommon neoplasms apparently derived from Schwann cells. The growth of these tumors causes displacement and compression of the nerve of origin.
Freitas, Roseana de Almeida, Freitas, Valéria Souza, Pinto, Leão Pereira, Santos, Pedro Paulo de Andrade, Souza, Lelia Batista de   +4 more
core   +1 more source