Results 81 to 90 of about 26,051 (179)

Expanding the Anatomical Distribution of PRRX1::KMT2D Fusion Mesenchymal Neoplasms: A Rare Mediastinal Case Report

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background PRRX1‐rearranged mesenchymal neoplasms are rare soft tissue tumors with a predilection for the superficial subcutaneous tissue. The PRRX1::KMT2D fusion variant is exceptionally rare, with only three previously reported cases, all of which were located in the intermuscular regions.
Weixiang Zhong, Yu Deng, Ke Sun
wiley   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

open access: yesJournal of Surgical Oncology, Volume 133, Issue 4, Page 486-510, March 15, 2026.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado   +9 more
wiley   +1 more source

A unique case of epithelioid schwannoma; rare soft tissue tumor

open access: yesHuman Pathology: Case Reports, 2018
Epithelioid schwannoma is a rare histological subtype of schwannoma that can cause diagnostic challenges. Most reported cases in the literature were located predominantly in the dermis and subcutaneous tissue of the extremities and trunk.
Haneen Al-Maghrabi, Njoud Aldardeir
doaj   +1 more source

Immunoreactivity for CD34, Desmin, Keratins, KIT, Alpha‐Smooth Muscle Actin, S100, and Vimentin in Malignant Mesenchymal Neoplasms in Guinea Pigs: A Series of 62 Cases From a Single Institution

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Immunohistochemical expression of CD34, desmin, keratin AE1/AE3, keratin 8/18, KIT, SMA, S100, and vimentin in normal guinea pig skin serving as both positive and negative external tissue control. All images immunohistochemical staining, 200× magnification, scale bar 100 µm. (A) CD34 stained only vascular endothelium (arrow).
Jiří Lenz   +3 more
wiley   +1 more source

Identification of a distinct epigenetic subgroup with inferior PFS in intracranial mesenchymal tumors with FET::CREB fusion

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin   +12 more
wiley   +1 more source

A case report of rectal schwannoma and literature review

open access: yes结直肠肛门外科
Schwannoma is a rare tumor originating from Schwann cells, typically occurring in the peripheral nervous system. It is seldom found in the gastrointestinal tract and is particularly rare in the rectum. In recent years, with advances in imaging techniques,
Song Ziqiang   +4 more
doaj   +1 more source

Meflin/ISLR is a meningeal cell‐specific marker involved in the development of meninges and meningioma progression

open access: yesBrain Pathology, Volume 36, Issue 2, March 2026.
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki   +13 more
wiley   +1 more source

The tumour immune microenvironment is enriched but suppressed in vestibular schwannoma compared to meningioma: therapeutic implications for NF2-related schwannomatosis

open access: yesActa Neuropathologica Communications
Currently there are no therapeutic agents that are effective against both vestibular schwannoma and meningioma, the two most common tumour types affecting patients with the rare tumour predisposition syndrome NF2-related schwannomatosis. This study aimed
Grace E. Gregory   +9 more
doaj   +1 more source

Schwannoma of the nasal tip: case report and short review of literature

open access: yesTurkish Archives of Otorhinolaryngology, 2009
A case of nasal tip Schwannoma is presented in this paper. Schwannoma is usually a benign neoplasm which is composed of Schwann cells. A 14-year-old boy had suffered from progressive swelling of the nasal tip over 4 months.
Müzeyyen Yıldırım   +4 more
doaj   +1 more source

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla   +8 more
wiley   +1 more source

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