Results 31 to 40 of about 1,956 (168)
Clinical response to bevacizumab in schwannomatosis [PDF]
Neurology, 2014 Schwannomatosis is a neurogenetic syndrome characterized by schwannomas throughout the peripheral nervous system without bilateral vestibular schwannomas (VS) or germline neurofibromatosis 2 (NF2) mutation.1 Management is difficult due to large tumor burden and treatment-resistant pain.
Blakeley, Jaishri +7 more
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Schwannoma of the external auditory canal as a part of schwannomatosis
Acta Oto-Laryngologica Case Reports, 2019 We experienced a very rare case, which we believe to be sporadic schwannomatosis, in which a 49-year-old female patient presented with conductive hearing loss due to a subcutaneous tumor in the right external auditory canal and the symptoms were ...
Saeko Matsuzaki +3 more
doaj +1 more source
Left atrial schwannoma in schwannomatosis: a case report
Surgical Case Reports, 2021 Background Primary cardiac schwannoma in the left atrium and schwannomatosis are rare diseases. Case presentation We report the case of a 46-year-old asymptomatic man who had tumor resection for parapharyngeal schwannoma at another institute 1 year ago ...
Kenji Yokoyama +2 more
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Recurrent orbital schwannomas: clinical course and histopathologic correlation
BMC Ophthalmology, 2012 Background Schwannomas are slow-growing typically encapsulated tumors composed of differentiated Schwann cells, the primary class of peripheral glial cells.
Kron Michelle +4 more
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Whole-body imaging in schwannomatosis [PDF]
Neurology, 2011 A 23-year-old man with schwannomatosis1 was imaged with whole-body MRI and 18F FDG-PET to assess the extent of disease prior to initiating systemic therapy for new and growing tumors. The patient had undergone multiple prior resections of schwannomas from peripheral nerves. …
Avneesh, Chhabra, Jaishri, Blakely
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MUTATIONS OF THE SMARCB1 GENE IN HUMAN CANCERS
Alʹmanah Kliničeskoj Mediciny, 2017 In the recent years, the full exome sequencing helped to reveal a set of mutations in the genes that are not oncogenes or tumor suppressor genes by definition, but play an important role in carcinogenesis and encode proteins involved in chromatin ...
D. S. Mikhaylenko +3 more
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Schwannomatosis of the tibial nerve
International Journal of Research in Orthopaedics, 2021 <p class="abstract">Schwannoma is the most common type of benign tumor arising from the sheaths of the peripheral nerves. It occurs as a solitary tumor in most cases, but when it appears in multiple forms, it is necessary to differentiate it from plexiform schwannoma, schwannomatosis, neurofibroma and malignant peripheral nerve tumors.
Jin Woo Jin +2 more
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Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Oncology and TherapyNeurofibromatosis type 2 (NF2)-related schwannomatosis is a rare autosomal dominant monogenic disorder caused by mutations in the NF2 gene. The hallmarks of NF2-related schwannomatosis are bilateral vestibular schwannomas (VS).
Ruofei Yuan +3 more
doaj +1 more source
Schwannomatosis of a Single Intercostal Nerve: A Case Report
Kaohsiung Journal of Medical Sciences, 2009 Schwannomatosis is a rare form of neurofibromatosis and is characterized by more than one schwannoma without any sign of neurofibromatosis. We report a case of a 60-year-old male patient admitted with progressive chest discomfort who was found to have ...
Jui-Wen Lee, Jane-Yi Hsu
doaj +1 more source