Results 41 to 50 of about 3,249 (205)

Patient-reported outcomes of pain and physical functioning in neurofibromatosis clinical trials. [PDF]

, 2016
ObjectiveTumors and other disease complications of neurofibromatosis (NF) can cause pain and negatively affect physical functioning. To document the clinical benefit of treatment in NF trials targeting these manifestations, patient-reported outcomes ...
Baldwin, A, Bergner, AL, Dudley, WN, Franklin, B, Gardner, KL, Hanemann, CO, HIngtgen, CM, Martin, S, Merker, VL, Schorry, E, Soloman, SE, Thompson, HL, Tonsgard, JH, Walsh, K, Wolters, PL   +14 more
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Recurrent Schwannomatosis of the Hand

HAND, 2020
Background: Peripheral nerve sheath tumors (PNSTs) are neoplastic soft tissue masses generated from the abnormal proliferation of Schwann cells. Often, these tumors occur in isolation and are known as schwannomas or neurilemmomas. The presence of multiple schwannomas is known as schwannomatosis. The purpose of this article is 2-fold: (1) to review the
Razvan Nicolescu, Nikhil A. Agrawal, Rowland W. Pettit, David T. Netscher   +3 more
openaire   +3 more sources

The Molecular Pathogenesis, Diagnostic Criteria, Symptoms, Clinical Manifestations, and Gene-Based Therapeutic Approaches in Neurofibromatosis [PDF]

مجله دانشگاه علوم پزشکی گرگان, 2023
Neurofibromatosis (NF) is a heterogeneous group of tumor predisposition syndromes that lead to malignancy in the central and peripheral nervous systems.
Fatemeh Shahraki, Morteza Oladnabi
doaj  

Neurocognitive outcomes in neurofibromatosis clinical trials [PDF]

, 2016
Neurofibromatosis type 1 (NF1) is associated with neurocognitive deficits that can impact everyday functioning of children, adolescents, and adults with this disease.
de Blank, P, Gray, LS, Hanemann, CO, Hardy, KK, Janusz, J, Klein-Tasman, BP, Martin, S, Payne, JM, Semerjian, C, Solomon, SE, Thompson, HL, Toledo-Tamula, MA, Ullrich, N, Walsh, KS, Wolters, PL   +14 more
core   +2 more sources

PTPN11 mutation manifesting as LEOPARD syndrome associated with hypertrophic plexi and neuropathic pain. [PDF]

, 2015
BACKGROUND: LEOPARD syndrome (LS) belongs to the family of neuro-cardio-facio-cutaneous syndromes, which include Neurofibromatosis-1 (NF1), Noonan syndrome, Costello Syndrome, cardio-facio-cutaneous syndrome, Noonan-like syndrome with loose anagen hair ...
Croquelois, A., Kuntzer, T., Spatola, M., Wider, C.   +3 more
core   +1 more source

Schwannoma of the external auditory canal as a part of schwannomatosis

Acta Oto-Laryngologica Case Reports, 2019
We experienced a very rare case, which we believe to be sporadic schwannomatosis, in which a 49-year-old female patient presented with conductive hearing loss due to a subcutaneous tumor in the right external auditory canal and the symptoms were ...
Saeko Matsuzaki, Naoki Oishi, Satoko Wakabayashi, Kaoru Ogawa   +3 more
doaj   +1 more source

Recurrent orbital schwannomas: clinical course and histopathologic correlation

BMC Ophthalmology, 2012
Background Schwannomas are slow-growing typically encapsulated tumors composed of differentiated Schwann cells, the primary class of peripheral glial cells.
Kron Michelle, Bohnsack Brenda L, Archer Steven M, McHugh Jonathan B, Kahana Alon   +4 more
doaj   +1 more source

Clinical response to bevacizumab in schwannomatosis [PDF]

Neurology, 2014
Schwannomatosis is a neurogenetic syndrome characterized by schwannomas throughout the peripheral nervous system without bilateral vestibular schwannomas (VS) or germline neurofibromatosis 2 (NF2) mutation.1 Management is difficult due to large tumor burden and treatment-resistant pain.
Blakeley, Jaishri, Schreck, Karisa C, Evans, D Gareth; id_orcid 0000-0002-8482-5784, Korf, Bruce R, Zagzag, David, Karajannis, Matthias A, Bergner, Amanda L, Belzberg, Allan J   +7 more
openaire   +2 more sources

Left atrial schwannoma in schwannomatosis: a case report

Surgical Case Reports, 2021
Background Primary cardiac schwannoma in the left atrium and schwannomatosis are rare diseases. Case presentation We report the case of a 46-year-old asymptomatic man who had tumor resection for parapharyngeal schwannoma at another institute 1 year ago ...
Kenji Yokoyama, Tomoya Yoshizaki, Dai Tasaki   +2 more
doaj   +1 more source

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. [PDF]

, 2019
Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The Saccharomyces cerevisiae RSC (Remodeling the Structure of Chromatin) complex, a member of the SWI/SNF chromatin ...
Afonine, Afonine, Allen, Angus-Hill, Ashkenazy, Ashkenazy, Asturias, Badis, Buchan, Buchan, Cairns, Cairns, Campsteijn, Chaban, Chambers, Chatterjee, Clapier, Clapier, Côté, Da, Dechassa, Duan, Dutta, Dürr, El-Gebali, Emsley, Erkina, Filippakopoulos, Goddard, Han, Jones, Jones, Kadoch, Kasten, Klein-Brill, Krietenstein, Kuryan, Leschziner, Leschziner, Li, Liu, Lopéz-Blanco, Mashtalir, Morin, Nagai, Nakane, Ng, Patel, Pettersen, Puig, Saha, Sammak, Schorb, Schubert, Sen, Shim, Sievers, Skiniotis, Smith, Suloway, Söding, Tan, Tsunaka, Ungar, Valencia, Wagner, Wang, Wilson, Xia, Yan, Yang, Ye, Yen, Zhang, Zhang, Zhang, Zheng, Zivanov, Zivanov, Zukin   +79 more
core   +3 more sources