ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler+43 more
wiley +1 more source
Zu viele Schulden, zu wenig sozial Das sozialpolitische Drei-Säulen-Konzept als Alternative zu neuen Steuern und ...
Weigelt, Kurt, Bodmer, Frank
openaire +1 more source
Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif+17 more
wiley +1 more source
ICU‐EEG Pattern Detection by a Convolutional Neural Network
ABSTRACT Objective Patients in the intensive care unit (ICU) often require continuous EEG (cEEG) monitoring due to the high risk of seizures and rhythmic and periodic patterns (RPPs). However, interpreting cEEG in real time is resource‐intensive and heavily relies on specialized expertise, which is not always available.
Giulio Degano+5 more
wiley +1 more source
Dr. L. Rabenhorst's Kryptogamen‐Flora von Deutschland, Oesterreich und der Schweiz. Vierter Band: Die Laubmoose von K. Gustav Limpricht. 1. Lieferung: Einleitung. 2. Lieferung: Einleitung. Sphagnaceae. Mit zahlreichen in den Text eingedruckten Abbildungen. Leipzig, Eduard Kummer, 1885. 128 S. in 8 und II. Preis jeder Lieferung: 2 Mk. 40 Pf [PDF]
A. Geheeb
openalex +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo+8 more
wiley +1 more source
Verbände in Deutschland: Potenzial und Relevanz für den Meeting-Markt Schweiz [PDF]
Grosse Verbandskongresse bringen einem Standort Wertschöpfung und Ansehen, fördern neben den ökonomischen Effekten aber auch den Wissenstransfer in einer Region. Sie fungieren als Schaufenster für die regionale Ökonomie und Wissenschaft.
Banz, Samira, Wilk, Rolf
core
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
L'édition française de la "Geographie der Schweiz" [PDF]
H. Onde
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