Results 21 to 30 of about 107,253 (283)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Der Einfluss des Bildungsniveaus von Frauen auf das Scheidungsverhalten in der Schweiz, 1952–2013
Swiss Journal of Sociology, 2017 Der Beitrag zeigt auf, dass von 1952 bis 2003 in der Schweiz für hoch gebildete Frauen die höchste Scheidungswahrscheinlichkeit bestand. Von 2004 bis 2013 hingegen sind keine bildungsspezifischen Unterschiede hinsichtlich des Scheidungsverhaltens mehr ...
Villiger Simone
doaj +1 more source
The relationship between flexible and self-regulated learning in open and distance universities
International Review of Research in Open and Distributed Learning, 2012 Flexibility in learning provides a student room for volitional control and an array of strategies and encourages persistence in the face of difficulties.
Per Bernard Bergamin +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Schweiz. Unfallversicherungs A.G. in Winterthur
SCHWEIZ. UNFALLVERSICHERUNGS A.G. IN WINTERTHUR Schweiz. Unfallversicherungs A.G. in Winterthur ( -
Schweiz. Unfallversicherungs A.G.
core +5 more sources
International Journal of Health Professions, 2022 Interprofessionelle Lehre (IPL) bedeutet, dass Studierende verschiedener Professionen mit-, von- und übereinander lernen. 2019 wurde im Kanton Zürich ein interprofessioneller Ausbildungstag (IPE-Tag) mit 68 Studierenden und acht Dozierenden über acht ...
Osterwalder Phylicia +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Vom gemessenen zum angemessenen Körper - Human Enhancement als historischer Prozess [PDF]
, 2012 An manchen Tagen sind Körper und Psyche in Bestform: Die Kommunikation gelingt eloquent, Konzentration und Ausdauer lassen ausgezeichnete Leistungen zu. Können pharmakologische Substanzen einem solchen Zustand auf die Sprünge helfen? Unter dem Stichwort «
Ritzmann, Iris; https://orcid.org/
core +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source