Results 31 to 40 of about 282,906 (343)

On the trails of Josias Braun-Blanquet II : first results from the 12th EDGG Field Workshop studying the dry grasslands of the inneralpine dry valleys of Switzerland [PDF]

, 2020
The 12th EDGG Field Workshop took place from 11 to 19 May 2019, organised by the Vegetation Ecology Group of the Institute of Natural Resource Sciences (IUNR) of the Zurich University of Applied Sciences (ZHAW). Like in the 11th Field Workshop in Austria,
Babbi, Manuel, Boch, Steffen, Catalano, Chiara, Cykowska-Marzencka, Beata, Dembicz, Iwona, Dengler, Jürgen, Eggenberg, Stefan, Gehler, Jamyra, Guarino, Riccardo, Monigatti, Martina, Moysiyenko, Ivan, Pachlatko, Jonathan, Riedel, Susanne, Vynokurov, Denys, Willner, Wolfgang   +14 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Wissen für die Praxis [PDF]

, 2007
Dank der Zusammenarbeit von elf europäischen Ländern im ERA-NET CORE Organic kam Transparenz in die Bio-Landbauforschung. Wie sieht die Situation in Deutschland, Österreich und der Schweiz aus?
Niggli, Urs, Willer, Helga
core  

Perinatal mental disorders in Switzerland : prevalence estimates and use of mental-health services [PDF]

, 2017
Background: Perinatal mental disorders (PMDs) are the most common complication of pregnancy and the first postpartum year. Since PMD prevalence and use of mental-health services by perinatal women in Switzerland are unknown, we analysed existing health ...
Bachmann, Nicole, Berger, Anke, Cignacco, Eva, Erdin, Rebekka, Oelhafen, Stephan, Reich, Oliver, Signorell, Andri   +6 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Das Personenfreizügigkeitsabkommen Schweiz-EU/EFTA und das Wachstum des BIP pro Kopf in der Schweiz: Bericht zuhanden des Bundesamtes für Migration (BFM) [PDF]

, 2012
Dieser Bericht beleuchtet, wie das Personenfreizügigkeitsabkommen (FZA) der Schweiz mit den EU/EFTA-Staaten das Einkommenswachstum in der Schweiz in den letzten Jahren beeinflusst hat.
Siegenthaler, Michael, Sturm, Jan-Egbert
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The academization of the health professions in Switzerland: facts and figures / Akademisierung der Gesundheitsberufe in der Schweiz: Zahlen und Fakten

International Journal of Health Professions, 2021
Dieser Beitrag stellt die Ausbildungssystematik in der Schweiz vor und ordnet die Gesundheitsberufe darin ein. Statistiken zu Studierenden der Gesundheitsberufe ab dem Jahr 2000 bis 2020 geben einen Einblick in die zahlenmässige Entwicklung.
Bucher Thomas
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source