Results 101 to 110 of about 65,822 (289)

The potential role of sciatic nerve stiffness in the limitation of maximal ankle range of motion

, 2018
It is a long held belief that maximal joint range of motion (ROM) is restricted by muscle tension. However, it exists indirect evidence suggesting that this assumption may not hold true for some joint configurations where non-muscular structures, such as
Freitas, Sandro, Freitas, Sandro R., Lacourpaille, Lilian, Andrade, Ricardo J, Andrade, Ricardo J., Hug, François, Le Sant, Guillaume, Nordez, Antoine, Gross, Raphäel, McNair, Peter, Andrade, Ricardo, Freitas, Sandro R   +11 more
core   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Salvage of Iatrogenic Sciatic Nerve Injury Caused by Operatively Treated Acetabular Fractures: Two Cases and Literature Review

Orthopaedic Surgery
Background While sciatic nerve injury has been described as a complication of acetabular fractures, iatrogenic nerve injury remains sparsely reported.
Peng Zhang, Fulin Tao, Wenhao Song, Shuai Wu, Dawei Wang, Dongsheng Zhou, Fanxiao Liu   +6 more
doaj   +1 more source

Selection of sciatic nerve injury models: implications for pathogenesis and treatment

Frontiers in Neurology
Sciatic nerve injury is one of the most frequent peripheral nerve injuries in the world. The loss of motor and sensory function, along with chronic pain caused by sciatic nerve injury, significantly impacts patients’ quality of life.
Pinxi Zhou, Ruhan Zhang, Liangmei Xian, Le Ning, Penghui Lu, Qianyan Liu, Mi Liu   +6 more
doaj   +1 more source

Investigation of Sciatic Nerve Surgical Anatomy in Dogs and Cats: A Comparative Cadaveric Study [PDF]

, 2017
Objective: Dogs and cats with traumatic or iatrogenic partial sciatic nerve lesions frequently have disparate clinical signs. Cats commonly walk with a plantigrade posture in the affected pelvic limb, which is rarely observed in dogs.
Dayer, Thomas, Rohrbach, Helene, Forterre, Simone, Stoffel, Michael Hubert, Forterre, Franck   +4 more
core  

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

miR-sc3, a Novel MicroRNA, Promotes Schwann Cell Proliferation and Migration by Targeting Astn1

Cell Transplantation, 2016
MicroRNAs (miRNAs, miRs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level. We have previously identified a group of novel miRNAs in proximal sciatic nerve after sciatic nerve transection by Solexa sequencing, and ...
Sheng Yi, Shanshan Wang, Qing Zhao, Chun Yao, Yun Gu, Jie Liu, Xiaosong Gu, Shiying Li   +7 more
doaj   +1 more source

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration.

, 2012
The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration.
Jenkins, Billy, Turmaine, Mark, Mirsky, Rhona, Quintes, Susanne, Wicher, GK, Wilton, Daniel K., Chabrol, Elodie, Latouche, Morwena, Chabrol, E, Banerjee, Ambily, Behrens, A, Mirsky, R, Woodhoo, Ashwin, Jenkins, B, Mitter, Richard, Quintes, S, Turmaine, M, Greensmith, L, Jessen, Kristján R., Wicher, Grzegorz K., Woodhoo, A, Mitter, R, Behrens, Axel, Raivich, Gennadij, Wicher, Grzegorz K.,, Latouche, M, Banerjee, Annbily, Arthur-Farraj, PJ, Wilton, DK, Banerjee, A, Rahman, Mary, Jessen, KR, Rahman, M, Arthur-Farraj, Peter J., Greensmith, Linda, Raivich, G   +35 more
core   +1 more source

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

BMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang, Lusen Shi, Xinhui Liu, Zhong Zhuang, Zhichao Feng, Chunhui Sun, Jingang Wang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shuping Wang, Hengxing Zhou, Na Ren   +11 more
wiley   +1 more source

A novel method for sciatic nerve decompression: Cadaveric feasibility study with potential application to patients with piriformis syndrome

Translational Research in Anatomy, 2015
Introduction: Approaches for proximal sciatic nerve decompression use a transgluteal route, but are associated with morbidity and complications. An alternative anterior approach to the sciatic nerve was designed.
Richard Isaiah Tubbs, James C. Barton, III, Caroline C. Watson, Theofanis Kollias, Robert J. Ward, Marios Loukas, Nicholas M. Barbaro, Aaron A. Cohen-Gadol   +7 more
doaj   +1 more source