An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni +6 more
wiley +1 more source
Preventive Treatment With Ceftriaxone Attenuates Neuropathic Pain and Anxiety-Like Behaviour in a Mouse Model of Partial Sciatic Nerve Ligation. [PDF]
Braconnier P +5 more
europepmc +1 more source
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato +7 more
wiley +1 more source
Neuroma Prevention with a Novel In Situ Forming Hydrogel in a Rat Sciatic Nerve Model. [PDF]
Campbell S +4 more
europepmc +1 more source
Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota +10 more
wiley +1 more source
Proximal Hamstring-Related Sciatic Nerve Entrapment Presenting as Recurrent Hamstring Strain in a Professional Footballer: A Case Report. [PDF]
Sawaf A.
europepmc +1 more source
Purpose To evaluate midterm outcomes of structural allograft reconstruction in patients with chronic proximal hamstring avulsion injuries. Methods This was a retrospective cohort study (minimum 2‐year follow‐up) including patients who underwent allograft surgical reconstruction for proximal hamstring avulsion injuries between 2016 and 2023. The primary
Nicolas Lefèvre +8 more
wiley +1 more source
The Role of Plant-Derived Compounds on the Cervical Spinal Cord After Sciatic Nerve Transection in Diabetic Rats. [PDF]
Marangoz AH +7 more
europepmc +1 more source
ABSTRACT Secondary infection can coexist with and obscure an underlying soft‐tissue sarcoma. A deep mass that persists or progresses despite drainage and appropriate antibiotics, especially with progressive neurological deficit, warrants image‐guided core biopsy and sarcoma‐center referral before further surgery.
Baraa Nassar +4 more
wiley +1 more source
Neurological tissue dissection techniques in mouse models for reproducible scientific results: Brain, spinal cord, cerebrospinal fluid, and sciatic nerve. [PDF]
Crew L, Seerley A, McElroy S, Panter AG.
europepmc +1 more source

