Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song +4 more
wiley +1 more source
Effect of liposomal bupivacaine for sciatic nerve block on opioid use in patients undergoing maxillofacial reconstruction with free fibular flap: a randomized, controlled trial. [PDF]
Wu HY +4 more
europepmc +1 more source
Saphenous and sciatic nerve block to treat acute lower limb ischemic pain in the emergency department. [PDF]
Ransford G +4 more
europepmc +1 more source
Time‐Restricted Feeding Alters Behavior in a Sex‐Specific Manner in Mice With Neuropathic Pain
Time‐restricted feeding (TRF) alleviates anxiety‐like behavior in male mice with neuropathic pain (NP), but not in females. Upon nerve injury, TRF altered the diurnal expression of transcripts in the hypothalamus. These findings suggest that TRF should be explored as a new therapeutic approach to alleviate the comorbid anxiety in NP.
Manqing Wen +3 more
wiley +1 more source
Lumbosacral Erector Spinae Plane Block Versus Psoas Muscle Compartment with Sciatic Nerve Block for Anesthesia for Unilateral Lower Limb Operations in Critically Ill Patients: A Randomized Open-Label Study. [PDF]
R Elbasyouny M +5 more
europepmc +1 more source
Estimation of the minimum effective volume of 0.5% bupivacaine for ultrasound-guided popliteal sciatic nerve block in diabetic patients with neuropathy. [PDF]
Parthasarathy S, Chanda A, Saravanan B.
europepmc +1 more source
Sciatic nerve block made easy for resident trainers [PDF]
Enas Abd el motlb +2 more
openalex +1 more source
The effects of ZnO, fullerene C60 and polyaniline (PANI) nanoparticles in hybrid nerve conduits are explored. The composites show enhanced electrical conductivity, permeability to physiological fluids and mechanical stability. The biocompatibility of composites is confirmed by in vivo and in vitro studies.
Liudmyla Sukhodub +7 more
wiley +1 more source

