Results 91 to 100 of about 220,539 (258)

Enhanced c-Fos expression in the central amygdala correlates with increased thigmotaxis in rats with peripheral nerve injury [PDF]

, 2015
Pain is associated with affective, cognitive and sensory dysfunction. Animal models can be used to observe ethologically relevant behaviours such as thigmotaxis, giving insight into how ongoing sensory abnormalities influence natural rodent behaviours ...
Rice, ASC
core   +1 more source

Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function [PDF]

, 2011
Mitochondrial dysfunction is a common cause of peripheral neuropathies. While the role of neuron and axonal mitochondria in peripheral nerve disease is well appreciated, whether Schwann cell (SC) mitochondrial deficits contribute to peripheral ...
Baloh, Robert H, Golden, Judith P, Hunter, Daniel A, Milbrandt, Jeffrey, Schmidt, Robert E, Viader, Andreu   +5 more
core   +2 more sources

Histopathological and behavioral evaluations of the effects of crocin, safranal and insulin on diabetic peripheral neuropathy in rats [PDF]

Avicenna Journal of Phytomedicine, 2015
Objectives: Crocin and safranal, the major constituents of saffron, exert neuroprotective effects. In the present study, we investigated the effects of crocin and safranal  (alone or in combination with insulin) on peripheral neuropathy in diabetic rats.
Amir Farshid, Esmaeal Tamaddonfard
doaj  

Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. [PDF]

, 2018
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and dose-limiting side effect of cancer treatment that affects millions of cancer survivors throughout the world and current treatment options are extremely limited by their side effects ...
Mackie, Ken, Marty, Vincent N, Mulpuri, Yatendra, Munier, Joseph J, Schmidt, Brian L, Seltzman, Herbert H, Spigelman, Igor   +6 more
core   +1 more source

Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats

Journal of Pharmacological Sciences, 2015
Bortezomib, an effective anticancer drug for multiple myeloma, often causes peripheral neuropathy which is mainly characterized by numbness and painful paresthesia.
Shota Yamamoto, Takehiro Kawashiri, Hitomi Higuchi, Kuniaki Tsutsumi, Soichiro Ushio, Takanori Kaname, Masafumi Shirahama, Nobuaki Egashira   +7 more
doaj   +1 more source

The role of thrombin in the pathogenesis of diabetic neuropathy.

PLoS ONE, 2019
Diabetic neuropathy is common and disabling despite glycemic control. Novel neuroprotective approaches are needed. Thrombin and hypercoagulability are associated with diabetes and nerve conduction dysfunction. Our aim was to study the role of thrombin in
Efrat Shavit-Stein, Ramona Aronovich, Constantin Sylantiev, Shany Guly Gofrit, Joab Chapman, Amir Dori   +5 more
doaj   +1 more source

Cryoglobulinaemic neuropathy: a further cause of bilateral sciatic neuropathy

International Archives of Medicine, 2008
Bilateral sciatic neuropathy is a rare condition and it has been described as a compression or entrapment neuropathy but it is an uncommon clinical manifestation due to necrotizing vasculitis. We report an unusual case of cryoglobulinaemic neuropathy in an elderly woman with no underlying infectious or neoplastic cause; acute bilateral sciatic ...
Pérez, Desireé, de la Torre, Ricardo, Carrio, Isabel, Pinto, Jesús, Morís, Germán   +4 more
openaire   +2 more sources

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration [PDF]

, 2015
Acknowledgements We are indebted to Jim Humphries, JennyCorrigan, LizDarley, Elizabeth Joynson, Natalie Walters, Sara Wells and the whole necropsy, histology, genotyping and MLC ward 6 teams at MRC Harwell for excellent technical assistance. We thank the
Abramov, Andrey Y., Acevedo-Arozena, Abraham, Bennet, David L. H., Beskina, Olga A., Brandner, Sebastian, Busam, Bharani Shiva, Carter, Sarah, Codner, Gemma, Corrochano, Silvia, Esapa, Christopher, Estabel, Jeanne, Fisher, Elizabeth M. C., Fratta, Pietro, Galino, Jorge, Greensmith, Linda, Groves, Michael, Hilton, Helen, Joyce, Peter I., Landman, Allison S., Lionikas, Arimantas, Mcgoldrick, Philip, Plagnol, Vincent, Ramirez-Solis, Ramiro, Ryder, Edward, Stewart, Michelle, Teboul, Lydia, Tucker, Jennifer, Wackerhage, Henning, White, Jacqueline K.   +28 more
core   +3 more sources

Effects of decompression on behavioral, electrophysiologic, and histomorphologic recovery in a chronic sciatic nerve compression model of streptozotocin-induced diabetic rats

Journal of Pain Research, 2017
Ping-Hui Wang,1 Cheng-Chang Yang,2 Wei-Ren Su,3 Po-Ting Wu,3 Shun-Chien Cheng,1 I-Ming Jou4 1Department of Orthopedics, Chi-Mei Medical Center, 2Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, 3Department of ...
Wang PH, Yang CC, Su WR, Wu PT, Cheng SC, Jou IM   +5 more
doaj  

Profound Neuropathy after Penetrating Transection of the Sciatic Nerve by Femoral Cerclage Wire: Illustrative Case and Management Strategy

Neurotrauma Reports
Sciatic nerve injury associated with total hip arthroplasty (THA) confers chronic and progressive disability. Mechanisms of injury are heterogeneous and management nuances are often case-specific.
John K. Yue, Jun Yeop Oh, Alexander A. Aabedi, Jia-Shu Chen, Kenneth X. Probst, Vinil N. Shah, Rosanna L. Wustrack, Line G. Jacques   +7 more
doaj   +1 more source