Results 81 to 90 of about 13,802 (202)

The role of thrombin in the pathogenesis of diabetic neuropathy.

PLoS ONE, 2019
Diabetic neuropathy is common and disabling despite glycemic control. Novel neuroprotective approaches are needed. Thrombin and hypercoagulability are associated with diabetes and nerve conduction dysfunction. Our aim was to study the role of thrombin in
Efrat Shavit-Stein, Ramona Aronovich, Constantin Sylantiev, Shany Guly Gofrit, Joab Chapman, Amir Dori   +5 more
doaj   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, Volume 18, Issue 7, Page 723-734, July 2026.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Executive summary of American Radium Society Appropriate Use Criteria for the treatment of locoregionally recurrent rectal cancer

Cancer, Volume 132, Issue 12, 15 June 2026.
Abstract This literature‐based systematic review and associated guidelines provide evidence‐based paradigms for the management of locoregionally recurrent rectal cancer (LRRC). This multispecialty committee included gastrointestinal radiation and medical oncology, gastroenterology, radiology, and colorectal surgery.
Eric D. Miller, Krishan R. Jethwa, Eric Dozois, Zhaohui Jin, Gerard Abood, Dmitriy Akselrod, Joseph Attallah, D. Chamil Codipilly, Christopher J. Anker, Christopher L. Hallemeier, Leslie C. Hassett, Timothy Kennedy, Percy Lee, Diane C. Ling, Neil B. Newman, Navesh Sharma, William Small Jr., Leila Tchelebi, Suzanne Russo   +18 more
wiley   +1 more source

Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect

Journal of Pharmacological Sciences, 2019
Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, on oxaliplatin-induced peripheral neuropathy was investigated using both in vivo and in vitro models.
Takehiro Kawashiri, Shiori Shimizu, Nao Shigematsu, Daisuke Kobayashi, Takao Shimazoe   +4 more
doaj   +1 more source

Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice

Frontiers in Cellular Neuroscience
Extracellular vesicles (EVs) derived from healthy Schwann cells (SC-EVs) ameliorate peripheral neuropathy in diabetic mice and rescue sciatic nerve function in Schwann cell Dicer knockout mice in part via SC-EV cargo miRNAs.
Lei Wang, Xuerong Lu, Alexandra Szalad, Yi Zhang, Yanfeng Li, Mei Lu, Amy Kemper, Zhongwu Liu, Xian Shuang Liu, Michael Chopp, Michael Chopp, Zheng Gang Zhang   +11 more
doaj   +1 more source

Protective effects of methanolic extract of Juglans regia L. leaf on streptozotocin-induced diabetic peripheral neuropathy in rats

BMC Complementary and Alternative Medicine, 2017
Background Oxidative stress has a pivotal role in the pathogenesis and development of diabetic peripheral neuropathy (DPN), the most common and debilitating complications of diabetes mellitus. There is accumulating evidence that Juglans regia L.
Davood Nasiry, Ali Reza khalatbary, Hassan Ahmadvand, Fereshteh Talebpour Amiri, Esmaeil Akbari   +4 more
doaj   +1 more source

AN UNUSUAL CAUSE OF SCIATIC PAIN

, 2001
We describe a 47-year-old woman with sciatic neuropathy caused by compression of the sacral plexus by posterior shift of the uterus.
M. Murakami, H. Moriya, K. Takahashi, Y. Murata   +3 more
core   +1 more source

Native computed tomography in the diagnosis of post-traumatic sciatic neuropathy: a case report

Digital Diagnostics
Diagnosis of post-traumatic peripheral neuropathy relies on a combination of methods, including clinical examination, electroneuromyography, ultrasound, and magnetic resonance imaging.
Viktor P. Kondratyev, Andrey V. Dekopov, Alexey A. Tomskiy   +2 more
doaj   +1 more source

Postpartum Sciatic Neuropathy After Uncomplicated Vaginal Delivery. [PDF]

Neurohospitalist, 2023
Boutros N, Saba D, Trikamji B.
europepmc   +1 more source

The Effect of Co-administration of 4-Methylcatechol and Progesterone on Sciatic Nerve Function and Neurohistological Alterations in Streptozotocin-Induced Diabetic Neuropathy in Rats [PDF]

Cell Journal, 2011
Objective: Diabetic neuropathy is the most common complication of diabetes mellitusaffecting the nervous system. In this study, we investigated the in vivo effects of combinedadministration of 4-methylcatechol (4-MC) and progesterone (P) as a ...
Marzieh Panahi, Hamidreza Sameni
doaj