Acta Neuropathologica Communications, 2019 Recently, moderate prenatal alcohol exposure (PAE) was shown to be a risk factor for peripheral neuropathy following minor nerve injury. This effect coincides with elevated spinal cord astrocyte activation and ex vivo immune cell reactivity assessed by ...
Joshua J. Sanchez +9 more
doaj +1 more source
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]
, 2016 Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K +25 more
core +1 more source
Effects of imeglimin on experimental diabetic neuropathy in streptozotocin‐induced diabetic rats
Journal of Diabetes Investigation, EarlyView.Imeglimin exerted neuroprotective effects in a type 1 diabetic neuropathy model, improving sensory nerve conduction, sciatic nerve blood flow, and intraepidermal nerve fiber density. In vitro, imeglimin promoted neurite outgrowth in a DRG‐derived hybridoma cell line, supporting a direct neurotrophic action.
Wataru Nihei +10 more
wiley +1 more source
Protective effects of oxytocin and progesterone on paclitaxel-induced neuropathy in rats
Neurological Sciences and Neurophysiology, 2021 Objective: Paclitaxel (Ptx), used to treat cancer, still causes neuropathic pain and peripheral neuropathy today. This study was conducted to evaluate the effects of progesterone (Pg) and oxytocin (Oxy) on peripheral neuropathy rat model induced by Ptx ...
Mehmet Ekici, Muharrem Balkaya1
doaj +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
, 2006 We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR +6 more
core
Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infra-orbital blood-nerve barrier following chronic constriction injury? [PDF]
, 2017 BackgroundBlood–nerve barrier disruption is pivotal in the development of neuroinflammation, peripheral sensitization, and neuropathic pain after peripheral nerve injury.
Boucher, Yves +7 more
core +4 more sources
Expert Consensus on Trendelenburg Position Postless Hip Distraction Technique in Hip Arthroscopy
Orthopaedic Surgery, EarlyView.This work evaluates the Trendelenburg position postless hip distraction technique for hip arthroscopy, highlighting its safety, efficacy, cost‐effectiveness, and key clinical application points. ABSTRACT Postless hip distraction technique is a novel traction method for hip arthroscopy developed in recent years.
Yaoting Wang +11 more
wiley +1 more source
Journal of Pharmacological Sciences, 2008 We investigated the chronic functional and histopathological changes in the sciatic nerve and lens of streptozotocin (STZ)-diabetic rats and evaluated the preventive effects of ranirestat (AS-3201), a potent aldose reductase inhibitor, on these changes ...
Takafumi Matsumoto +5 more
doaj +1 more source
Acute sciatic neuropathy: "Saturday night palsy" [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2005 This is a case report of 25-year old, unemployed male, admitted to hospital due to acute onset of the left foot drop, subsequent walking difficulty and numbness of the left calf and foot. Symptoms began after prolonged sleep with previous heroin abuse by
Manigoda Miodrag +3 more
doaj +1 more source
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. [PDF]
, 2018 Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and dose-limiting side effect of cancer treatment that affects millions of cancer survivors throughout the world and current treatment options are extremely limited by their side effects ...
Mackie, Ken +6 more
core +1 more source