ABSTRACT Background and Aims Bortezomib‐induced peripheral neuropathy (BIPN) remains a common treatment side effect in patients with multiple myeloma (MM). Data from rodent models indicate a role of proinflammatory cytokines in BIPN pathophysiology, making them potential therapeutic targets.
Nadine Cebulla +18 more
wiley +1 more source
Low-intensity low-frequency pulsed ultrasound ameliorates sciatic nerve dysfunction in a rat model of cisplatin-induced peripheral neuropathy [PDF]
Busra Bilir-Yildiz +3 more
openalex +1 more source
Pemberian Citicoline Pada Tikus Cedera Saraf Mentalis: Ekspresi Gen SIRT1 Ganglion Trigeminal: the Administration of Citicoline on Rat Model with Mental Nerve Crush Injury: Gene Expression of Trigeminal Ganglion SIRT1 [PDF]
Cedera saraf perifer menyebabkan jumlah neuron menurun di ganglion sensorik, sehingga regenerasinya tidak baik. Pemberian Citicoline telah dilaporkan dapat memperbaiki kondisi fungsi motorik dan mencegah nyeri neuropati pada model tikus cedera saraf ...
Amri, I. (Imtihanah) +3 more
core
Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]
Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G. +5 more
core +1 more source
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo +8 more
wiley +1 more source
Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by Paclitaxel [PDF]
Peripheral neuropathy is a major side effect following treatment with the cancer chemotherapeutic drug paclitaxel. Whether paclitaxel-induced peripheral neuropathy is secondary to altered function of small diameter sensory neurons remains controversial ...
Basile, DP. +5 more
core +1 more source
Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect
Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, on oxaliplatin-induced peripheral neuropathy was investigated using both in vivo and in vitro models.
Takehiro Kawashiri +4 more
doaj +1 more source
Background Oxidative stress has a pivotal role in the pathogenesis and development of diabetic peripheral neuropathy (DPN), the most common and debilitating complications of diabetes mellitus. There is accumulating evidence that Juglans regia L.
Davood Nasiry +4 more
doaj +1 more source
Femoral and sciatic compression neuropathy
Abstract A case of a femoral neuropathy following anticoagulant therapy is presented. A combined femoral, obturator, and sciatic nerve palsy resulting from complications of atherosclerotic disease of the aorta and iliac arteries is also described.
openaire +2 more sources
Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice [PDF]
Elevated N-methyl-D-aspartate receptor (NMDAR) activity is linked to central sensitization and chronic pain. However, NMDAR antagonists display limited therapeutic potential because of their adverse side effects. Novel approaches targeting the NR2B-PSD95-
Chawla, Aarti +6 more
core +1 more source

