Results 101 to 110 of about 23,100 (268)

Cytokine Dynamics in Bortezomib‐Induced Peripheral Neuropathy: Challenges in Translating Preclinical Findings to Humans

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 1, March 2026.
ABSTRACT Background and Aims Bortezomib‐induced peripheral neuropathy (BIPN) remains a common treatment side effect in patients with multiple myeloma (MM). Data from rodent models indicate a role of proinflammatory cytokines in BIPN pathophysiology, making them potential therapeutic targets.
Nadine Cebulla   +18 more
wiley   +1 more source

Pemberian Citicoline Pada Tikus Cedera Saraf Mentalis: Ekspresi Gen SIRT1 Ganglion Trigeminal: the Administration of Citicoline on Rat Model with Mental Nerve Crush Injury: Gene Expression of Trigeminal Ganglion SIRT1 [PDF]

open access: yes, 2018
Cedera saraf perifer menyebabkan jumlah neuron menurun di ganglion sensorik, sehingga regenerasinya tidak baik. Pemberian Citicoline telah dilaporkan dapat memperbaiki kondisi fungsi motorik dan mencegah nyeri neuropati pada model tikus cedera saraf ...
Amri, I. (Imtihanah)   +3 more
core  

Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]

open access: yes, 2017
Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G.   +5 more
core   +1 more source

Differential roles of EA‐TRAPed cells in the anterior cingulate cortex across various intervention times in inflammatory pain

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 2, Page 329-343, February 2026.
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo   +8 more
wiley   +1 more source

Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by Paclitaxel [PDF]

open access: yes, 2011
Peripheral neuropathy is a major side effect following treatment with the cancer chemotherapeutic drug paclitaxel. Whether paclitaxel-induced peripheral neuropathy is secondary to altered function of small diameter sensory neurons remains controversial ...
Basile, DP.   +5 more
core   +1 more source

Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect

open access: yesJournal of Pharmacological Sciences, 2019
Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, on oxaliplatin-induced peripheral neuropathy was investigated using both in vivo and in vitro models.
Takehiro Kawashiri   +4 more
doaj   +1 more source

Protective effects of methanolic extract of Juglans regia L. leaf on streptozotocin-induced diabetic peripheral neuropathy in rats

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Oxidative stress has a pivotal role in the pathogenesis and development of diabetic peripheral neuropathy (DPN), the most common and debilitating complications of diabetes mellitus. There is accumulating evidence that Juglans regia L.
Davood Nasiry   +4 more
doaj   +1 more source

Femoral and sciatic compression neuropathy

open access: yesJournal of British Surgery, 1971
Abstract A case of a femoral neuropathy following anticoagulant therapy is presented. A combined femoral, obturator, and sciatic nerve palsy resulting from complications of atherosclerotic disease of the aorta and iliac arteries is also described.
openaire   +2 more sources

Disruption of nNOS-NOS1AP protein-protein interactions suppresses neuropathic pain in mice [PDF]

open access: yes, 2018
Elevated N-methyl-D-aspartate receptor (NMDAR) activity is linked to central sensitization and chronic pain. However, NMDAR antagonists display limited therapeutic potential because of their adverse side effects. Novel approaches targeting the NR2B-PSD95-
Chawla, Aarti   +6 more
core   +1 more source

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