Results 21 to 30 of about 23,100 (268)

Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic Peripheral Neuropathy

open access: yesStem Cells International, 2021
Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum-derivative chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors contributing to the development of OXL-induced peripheral neuropathy (OIPN ...
Anna Lethicia L. Oliveira   +7 more
doaj   +1 more source

The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy

open access: yesNeural Regeneration Research, 2023
Circular RNAs (circRNAs) play a vital role in diabetic peripheral neuropathy. However, their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.
Yu-Tian Liu   +12 more
doaj   +1 more source

The value of magnetic resonance neurography in evaluation of sciatic neuropathy

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Sciatic neuropathy is one of the most common neuropathies of the lower extremities. One of the most common presentations of sciatic neuropathy is foot drop and may also be associated with several other clinical (sensory and/or motor ...
Esraa Hessin Youssef Abd El-Azeem   +3 more
doaj   +1 more source

Pro-inflammatory cytokines and leukocyte integrins associated with chronic neuropathic pain in traumatic and inflammatory neuropathies: Initial observations and hypotheses

open access: yesFrontiers in Immunology, 2022
Leukocyte infiltration and persistence within peripheral nerves have been implicated in chronic nociception pathogenesis in murine peripheral neuropathy models.
Chaoling Dong, Eroboghene E. Ubogu
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

open access: yes, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila   +6 more
core   +2 more sources

Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice

open access: yesNeurobiology of Disease, 2012
Peripheral neuropathy is one of the most common complications of diabetes mellitus. Using a mouse model of diabetic peripheral neuropathy, we tested the hypothesis that thymosin β4 (Tβ4) ameliorates diabetes‐induced neurovascular dysfunction in the ...
Lei Wang   +9 more
doaj   +1 more source

Recurrent diffuse large B-cell lymphoma involving the sciatic nerve: A rare case report and review of the literature

open access: yesJournal of Medical Sciences, 2020
Neurolymphomatosis (NL) is an uncommon condition involving lymphomatous invasion of the cranial or spinal nerve roots. Sciatic nerve neuropathy and dysfunction represent a common cause of lower extremity symptoms in clinical practice.
Chun-Yi Lee   +4 more
doaj   +1 more source

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]

open access: yes, 2015
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky   +6 more
core   +2 more sources

Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]

open access: yes, 2018
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A.   +8 more
core   +1 more source

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