Results 31 to 40 of about 144,018 (191)

Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic Peripheral Neuropathy

open access: yesStem Cells International, 2021
Painful neuropathy is a common adverse effect of oxaliplatin (OXL), a platinum-derivative chemotherapeutic agent. Oxidative stress and mitochondrial dysfunction are key factors contributing to the development of OXL-induced peripheral neuropathy (OIPN ...
Anna Lethicia L. Oliveira   +7 more
doaj   +1 more source

Pediatric sciatic neuropathy presenting as painful leg: A case report and review of literature

open access: yesJournal of Pediatric Neurosciences, 2013
Introduction: Mononeuropathies, in general, are very uncommon in childhood. Sciatic neuropathy (SN) is probably underappreciated in childhood and likely to represent nearly one quarter of childhood mononeuropathies.
Manish Prasad   +3 more
doaj   +1 more source

Sciatic Nerve Intrafascicular Injection Induces Neuropathy by Activating the Matrix Modulators MMP-9 and TIMP-1

open access: yesFrontiers in Pharmacology, 2022
Background: Peripheral nerve block (PNB) under echo guidance may not prevent intrafascicular anesthetic injection-induced nerve injury. This study investigated whether unintended needle piercing alone, or the intrafascicular nerve injectant could induce ...
Kuang-Yi Tseng   +10 more
doaj   +1 more source

Isolated Sciatic Neuropathy as an Initial Manifestation of a High Grade B-cell Lymphoma: A Case Report and Literature Review.

open access: yes, 2016
Sciatic nerve neuropathy due to infiltrating of a high grade B-cell lymphoma is a very rare situation and has not often been reported. We report a case with a previous history of indolent lymphoma who presented with isolated sciatic nerve neuropathy and ...
He, Wenzhuan   +4 more
core   +3 more sources

The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy

open access: yesNeural Regeneration Research, 2023
Circular RNAs (circRNAs) play a vital role in diabetic peripheral neuropathy. However, their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.
Yu-Tian Liu   +12 more
doaj   +1 more source

Presumed septic sacroiliitis in a puppy with unilateral hind limb lameness and sciatic nerve neuropathy

open access: yesVeterinary Medicine and Science, 2021
A 5‐month‐old female entire Dachshund presented with an acute onset of left hind limb lameness following intense play. There were concurrent intermittent neurological deficits in the left hind limb, and pain in the lumbosacral region and on dorsal ...
Derniese Goh, Arthur House
doaj   +1 more source

Diabetic Peripheral Neuropathy Increases Electrical Stimulation Threshold of Sciatic Nerve: A Prospective Parallel Cohort Study

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Guang Ying Zhang, Yi Feng Chen, Wei Xin Dai, Dan Zhang, Yi Huang, Wen Zheng He, Cheng Xin Lin Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of ChinaCorrespondence: Cheng Xin ...
Zhang GY   +6 more
doaj  

The Possible Role of Propolis in Ameliorating Paclitaxel-Induced Peripheral Neuropathy in Sciatic Nerve of Adult Male Albino Rats [PDF]

open access: yesThe Egyptian Journal of Histology, 2017
Background: Paclitaxel is a neurotoxic chemotherapeutic agent. The sensorimotor peripheral neuropathy is a serious dose limiting complication of paclitaxel therapy. Propolis is a natural honeybee product collected from plants. It has broad biological and
Heba Elkaliny, Amira Kassab
doaj   +1 more source

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Leptin-deficient ob/ob mice are a model of type 2 diabetes induced peripheral neuropathy. Ob/ob mice exhibit obesity, insulin resistance, hyperglycaemia, and alterations of peripheral nerve fibres and endoneural microvessels. Here we test the
Joanna Kosacka   +7 more
doaj   +1 more source

Metformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway [PDF]

open access: yesArchives of Endocrinology and Metabolism
Objective: Diabetic neuropathy (DN) is an important complication of diabetes mellitus. Autophagy is considered to be potentially involved in the regulation of DN. Metformin is broadly utilized in the first-line treatment of diabetes.
Fangqin You   +4 more
doaj   +1 more source

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