Neurolymphomatosis (NL) is an uncommon condition involving lymphomatous invasion of the cranial or spinal nerve roots. Sciatic nerve neuropathy and dysfunction represent a common cause of lower extremity symptoms in clinical practice.
Chun-Yi Lee +4 more
doaj +1 more source
Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim +17 more
core +3 more sources
Delayed Onset Sciatic Nerve Palsy Secondary to Wound Hematoma following Anticoagulant Therapy Post-Bipolar Hemiarthroplasty - an Uncommon Complication: A Case Report [PDF]
A 58-year old female patient presented to us with a three months’ old fracture of the neck of femur. She underwent bipolar hemiarthroplasty. In the immediate postoperative period, she developed deep vein thrombosis for which she was started on ...
Balaji G, Sriharsha Y, Sharma D
doaj +1 more source
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib +3 more
core +2 more sources
Post-radiation sciatic neuropathy: a case report and review of the literature
Background Post-radiation peripheral neuropathy has been reported in brachial and cervical plexuses and the femoral nerve. Case presentation We describe a patient who developed post-radiation sciatic neuropathy after approximately 3 years and discuss the
Tirabosco Roberto +6 more
doaj +1 more source
Metformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway [PDF]
Objective: Diabetic neuropathy (DN) is an important complication of diabetes mellitus. Autophagy is considered to be potentially involved in the regulation of DN. Metformin is broadly utilized in the first-line treatment of diabetes.
Fangqin You +4 more
doaj +1 more source
Intrapelvic Nerve Entrapment Syndrome Caused by a Variation of the Intrapelvic Piriformis Muscle and Abnormal Varicose Vessels: A Case Report [PDF]
Entrapment neuropathy of the sciatic nerve and pudendal nerve are painful syndromes that are often overlooked by physicians. Laparoscopic surgical interventions for nerve entrapment syndromes of the posterior pelvis focus on removing the compression ...
Ahmet Kale +5 more
doaj +1 more source
Background: Peripheral nerve block (PNB) under echo guidance may not prevent intrafascicular anesthetic injection-induced nerve injury. This study investigated whether unintended needle piercing alone, or the intrafascicular nerve injectant could induce ...
Kuang-Yi Tseng +10 more
doaj +1 more source
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain [PDF]
Background: L-acetylcarnitine, a drug marketed for the treatment of chronic pain, causes analgesia by epigenetically up-regulating type-2 metabotropic glutamate (mGlu2) receptors in the spinal cord.
Battaglia, Giuseppe +10 more
core +1 more source
Insulin signal is one of the vital signaling cascade required for Schwann cells to myelinate the axons of peripheral nervous system (PNS). Myelin formation of peripheral nerve is a complex molecular event controlled by different neurotrophic and ...
Mallahalli S. Manu +2 more
doaj +1 more source

