Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor-Selective Deficits. [PDF]
GliaTo test the importance of lactate metabolism and shuttling between Schwann cells and neurons in the PNS, we selectively knocked out both LDHA and LDHB in motor neurons, sensory neurons, or Schwann cells. ABSTRACT Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS).
Bloom AJ +11 more
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Quantitative study and related factors analysis of sciatic neuropathy in type 2 diabetes mellitus patients by elastic imaging virtual tissue imaging quantification technique [PDF]
HereditasBackground The incidence of diabetic peripheral neuropathy (DPN) is increasing every year for type 2 diabetes mellitus (T2DM) patients, and diabetic polyneuropathy is a common type.
Ruixing Liu +4 more
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Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3. [PDF]
Ann NeurolRepeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Mato JP +7 more
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Sciatic neuropathy caused by a pressure ulcer [PDF]
Medicine, 2018 Sciatic neuropathy has various causes; however, cases in which a pressure ulcer led to sciatic neuropathy have not been reported to date.A 33-year-old woman with no pre-existing mobility problems visited our department with the chief complaint of an extensive pressure ulcer and necrosis in her right buttock. She had a medical history of being bedridden
Hwang, Jae Ha +3 more
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Endocrine JournalDyslipidemia has been considered a risk factor for diabetic peripheral neuropathy. Proprotein convertase subtilisin-like/Kexin 9 inhibitor (PCSK9) inhibitors are a new type of lipid-lowering drug currently in clinical use.
Na Cui +6 more
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Ischemic sciatic neuropathy and pelvic bone infarction following embolization of bilateral internal iliac artery aneurysms: A case report [PDF]
Radiology Case ReportsAn 82-year-old man underwent bilateral internal iliac artery (IIA) embolization for IIA aneurysms and endovascular repair for an abdominal aortic aneurysm.
Masaki Imaeda +4 more
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Shear wave elastography for quantitative assessment of nerve tissue stiffness after sciatic nerve decompression in diabetic rats [PDF]
Frontiers in NeurologyIntroductionDiabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. Surgical decompression of distal DPN has been shown to reduce ulceration and amputation rates, though recurrence risk persists, warranting postoperative ...
Dian-Cheng Li +4 more
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Cane sign: sciatic neuropathy appearance in magnetic resonance imaging [PDF]
, 2021 We present a patient with idiopathic sciatic neuropathy with demonstrative magnetic resonance imaging ...
Tan, Ersin +9 more
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Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice
Neurobiology of Disease, 2012 Peripheral neuropathy is one of the most common complications of diabetes mellitus. Using a mouse model of diabetic peripheral neuropathy, we tested the hypothesis that thymosin β4 (Tβ4) ameliorates diabetes‐induced neurovascular dysfunction in the ...
Lei Wang +9 more
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Lumbosacral Plexus Neuropathy-Idiopathic Sciatic Neuropathy: A Case Report [PDF]
, 2014 Although diabetic lumbosacral radiculoplexus neuropathy (LSRPN) is a well-known disease, clinical knowledge about non-diabetic idiopathic LSRPN is quite inadequate. LSRPN is rarely seen and does not require surgical treatment.
Kibar, Sibel, Evcik, Deniz, Ay, Saime
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