Results 131 to 140 of about 46,496 (324)

The Effect of Anti‐3‐Hydroxy‐3‐Methylglutaryl‐CoA Reductase (HMGCR) Human Autoantibodies on Muscle Regeneration in Mice

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Anti‐3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR) autoantibodies (aAbs) are pathogenic in immune‐mediated necrotizing myopathy (IMNM), partly through complement activation. C5 inhibition did not restore muscle strength in mice or patients with overt IMNM, suggesting additional pathogenic mechanisms.
Sarah Julien   +6 more
wiley   +1 more source

Steroid For Management Of Pseudo-othematoma [PDF]

open access: yes, 2011
Has conducted research on the use of steroids triamsinolon asetonid as pseudo-othematomamedical therapy. The purpose of this study was to determine the effectiveness triamsinolonasetonid. Prevention of the formation of serum in the lesion, so that pseudo-
Adiputra, N. (Nyoman)   +2 more
core  

Low‐value interventions to deimplement: A secondary analysis of a systematic review of low back pain clinical practice guidelines

open access: yesPM&R, EarlyView.
Abstract Objective To perform a secondary review of low back pain (LBP) clinical practice guidelines (CPG) identified in a recently conducted systematic review and to synthesize and summarize low‐value recommendations as practices that may be candidates for deimplementation.
Daniel Tai   +5 more
wiley   +1 more source

Pseudomeningocele Mimicking Sciatica

open access: yesWorld Neurosurgery
We report on an elderly woman with sciatica due to disc herniation, experiencing complete pain resolution following surgery. Four weeks later, she developed refractory, excruciating pain with foot palsy, prompting a lumbar magnetic resonance imaging that revealed no recurrent disc herniation.
Julien Jost, Lukas Andereggen
openaire   +3 more sources

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

Diagnostic Prediction Using Discomfort Drawings with IBTM [PDF]

open access: yes, 2016
In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms.
Bertilson, Bo C.   +3 more
core   +1 more source

Carbon Nanotube Hydrogels Reveal Threshold‐Dependent Regulation of Neuroblastoma Cell Growth and Maturation by Mechanical and Chemical Factors

open access: yesSmall Science, EarlyView.
Poly(vinyl alcohol)/carbon nanotube (PVA/CNT) hydrogels with unprecedented CNT loading (75% w/w) were engineered as 3D scaffolds for nerve regeneration. By tuning Young's modulus (YM), CNT concentration, and pore size, distinct thresholds controlling cell coverage were identified. Optimized scaffolds achieved > 70% coverage and upregulated β‐3‐tubulin (
Bahaa Daou   +3 more
wiley   +1 more source

Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues

open access: yesSmall Methods, EarlyView.
This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley   +1 more source

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