Results 131 to 140 of about 41,985 (321)

Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The study aimed to assess the feasibility of recording electrically evoked compound action potentials (ECAPs) from the rat spinal cord. To achieve this, we characterized electrophysiological responses of dorsal column (DC) axons from electrical stimulation and quantified the relationship between ECAP and motor thresholds (ECAPTs and
Birte Elisabeth Dietz, Dave Mugan, Quoc Chi Vuong, Ilona Obara   +3 more
wiley   +1 more source

Plant-Derived Medicines for Sciatica: A Comprehensive Review

Traditional and Integrative Medicine
Sciatica commonly refers to radicular leg pain which is mainly caused by lumbar disc herniation (LDH) and affects the daily functional ability of many patients in the world.
Narges Lavari, Niusha Esmaealzadeh, Roja Rahimi, Alireza Abbasian   +3 more
doaj   +1 more source

The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581)

BMC Musculoskeletal Disorders, 2017
Background Sciatica has a substantial impact on patients, and is associated with high healthcare and societal costs. Although there is variation in the clinical management of sciatica, the current model of care usually involves an initial period of ‘wait
Nadine E. Foster, Kika Konstantinou, Martyn Lewis, Reuben Ogollah, Kate M. Dunn, Danielle van der Windt, Ruth Beardmore, Majid Artus, Bernadette Bartlam, Jonathan C. Hill, Sue Jowett, Jesse Kigozi, Christian Mallen, Benjamin Saunders, Elaine M. Hay   +14 more
doaj   +1 more source

STUDIES OF ISCHAEMIC AND POST-ISCHAEMIC PARAESTHESIAE IN NORMAL SUBJECTS AND IN SCIATICA [PDF]

, 1952
John R. Marshall
openalex   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

Advanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali, Rocco Latorre, Raquel Tonello, David Poolman, Suwan Ding, Brian L. Schmidt, Nigel W. Bunnett, Kam W. Leong   +7 more
wiley   +1 more source

Sciatica due to extrapelvic heterotopic ossification: A case report

Journal of Medical Case Reports, 2008
Introduction Sciatica is a common problem, usually caused by disc herniation or spinal stenosis. Low back pain is also present in most cases. When sciatica is the unique clinical finding, especially in young patients, extraspinal pathology should be ...
Panagiotopoulos Elias C, Syggelos Spyros A, Plotas Athanasios, Tsigkas Gregorios, Dimopoulos Panagiotis   +4 more
doaj   +1 more source

Design and Application of Piezoelectric Conductive Smart Scaffold for Noninvasive Neural Tissue Regeneration via Custom‐Made In Vitro Mechano‐Stimulator

Advanced NanoBiomed Research, EarlyView.
Schematic illustration showing the design of the developed invitro mechano stimulator (IMS) and the electrospun nanofiber‐based piezoelectric and conductive nerve conduit (PCNC) that can self‐generate electrical stimulations analogous to neural tissues. IMS provided vital electrical cues for the neural cells to attach, align and proliferate on the PCNC
Afeesh Rajan Unnithan, Vignesh Krishnamoorthi Kaliannagounder, Nagamalleswara Rao Alluri, Chan Hee Park, Pandiyarasan Veluswamy, Arathyram Ramachandra Kurup Sasikala   +5 more
wiley   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

Angewandte Chemie International Edition, Accepted Article.
Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation in 1964, it has attracted the interest of synthetic organic chemists due to its exceptional polarity, complex architecture, and important biological activity.
Benedikt Nißl, Marcel Mülbaier, Francesca Grisoni, Dirk Trauner, Marcel Bermúdez, Clemens Dialer, David B. Konrad   +6 more
wiley   +1 more source

Axonal profiling of the common fibular nerve and its branches: Their functional composition and clinical implications

Clinical Anatomy, EarlyView.
Abstract The articular branch (Arb) from the common fibular nerve (CFN) plays a pivotal role in procedures such as genicular nerve blocks since it extensively innervates the anterolateral knee joint. It remains unclear whether the Arb can be classified as purely sensory, and understanding its axonal composition is critical to prevent muscle weakness ...
Taeyeon Kim, Tae‐Hyeon Cho, Shin Hyung Kim, Hun‐Mu Yang   +3 more
wiley   +1 more source

Vertebral pain in helicopter pilots [PDF]

Pathological forms of spinal pain engendered by piloting helicopters were clinically studied. Lumbalgia and pathology of the dorsal and cervical spine are discussed along with their clinical and radiological signs and ...
Auffret, R., Delahaye, R. P., Metges, P. J., VICENS   +3 more
core   +1 more source