Results 151 to 160 of about 25,360 (296)

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

open access: yesSmall Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez   +10 more
wiley   +1 more source

A new concept for evaluating muscle function in the lower extremities in cases of low back pain syndrome in anamnesis

open access: yesAnnals of Agricultural and Environmental Medicine, 2014
introduction. There are difficulties in objective evaluation of activity of the muscles in the lower extremities of patients after successful treatment of sciatica and pseudosciatica, when no clear clinical symptoms are detected.
Przemysław Lisiński   +8 more
doaj  

Association between lipid-lowering agents with intervertebral disc degeneration, sciatica and low back pain: a drug-targeted mendelian randomized study and cross-sectional observation

open access: yesLipids in Health and Disease
Background Abnormal lipid metabolism is linked to intervertebral disc degeneration (IVDD), sciatica, and low back pain (LBP), but it remains unclear whether targeted interventions can prevent these issues.
Chenxu Liu   +8 more
doaj   +1 more source

Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study

open access: yesVeterinary Record, EarlyView.
Abstract Background The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia ...
Xavier Torruella   +6 more
wiley   +1 more source

Chronic pain treatment experiences and barriers among opioid agonist treatment participants who inject drugs: A qualitative study

open access: yesAddiction, EarlyView.
Abstract Background and aim Co‐occurring chronic pain affects nearly half of people receiving opioid use disorder (OUD) treatment. Although this pain is often severe, it is usually inadequately managed. Stigma and clinical complexity associated with OUD are thought to further restrict access to pain care.
Jie Yang   +6 more
wiley   +1 more source

Infiltration between the popliteal artery and the capsule of the knee (IPACK) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a randomised controlled trial

open access: yesAnaesthesia, EarlyView.
Summary Introduction Infiltration between the popliteal artery and the capsule of the knee (IPACK) and the selective tibial nerve block both provide analgesia for the posterior aspect of the knee after anterior cruciate ligament reconstruction. This randomised controlled triple‐blinded trial tested the hypothesis that IPACK provides superior analgesia ...
Ludovic Beun   +5 more
wiley   +1 more source

Factors Affecting Surgical Outcomes Following Rotationplasty in Paediatric Sarcoma: A Literature Review

open access: yesANZ Journal of Surgery, EarlyView.
Rotationplasty is a durable limb‐salvage option for paediatric lower‐limb sarcoma. Across 58 studies and 1,217 patients, long‐term functional, psychosocial, and quality‐of‐life outcomes were favourable, often surpassing amputation and endoprosthetic reconstruction.
Rachel H. Ko   +2 more
wiley   +1 more source

Strength training during pregnancy for the prevention of gestational diabetes: A randomized trial in women with overweight or obesity

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Strength training during pregnancy safely improves maternal well‐being, increases physical activity, and reduces pregnancy symptoms, with a promising trend toward lower gestational diabetes. Abstract Introduction Evidence suggests that physical exercise may help prevent gestational diabetes mellitus, although available clinical trials are limited by ...
Teresa E. Santa Cruz   +3 more
wiley   +1 more source

Sciatica from Retroperitoneal Lymphoma

open access: yes, 1997
Back pain with sciatica is a common clinical syndrome that may be the expression of an uncommon pathological process. We describe a case of retroperitoneal lymphoma mimicking herniated lumbar disc.
윤덕미, 이윤우, 박원선
core  

Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat‐Dose Administration for up to 14 Days

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this Phase 1 study, linaprazan glurate (LG) demonstrated rapid onset of intragastric acid suppression, achieving a pH > 4 within 10 to 60 min, and maintained pH control, with a 24‐h pH > 4 holding time ratio above 95% at 50 mg and 75 mg twice‐daily doses. AUC and Cmax of linaprazan, the main metabolite of LG, increased in proportion to LG dose.
Kajsa Larsson   +7 more
wiley   +1 more source

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