Results 171 to 180 of about 20,394 (255)

Causal effect of education on low back pain, intervertebral disc degeneration and sciatica: Mendelian randomization study. [PDF]

Future Sci OA
Wu Z, Gong Y, Long H, Deng R, He J, Su M, Wang J, Gong K.   +7 more
europepmc   +1 more source

Nationwide Analysis of Sociodemographic Disparities in Health‐Related Quality of Life of Colon Cancer Survivors

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Health‐related quality of life (HRQOL) measures patients' overall well‐being and can help guide survivorship care. Evidence comparing individual patients' HRQOL pre‐ and post‐diagnosis is limited due to the unpredictable nature of cancer onset.
Kaelyn C. Cummins, Mohamad El Moheb, Susan J. Kim, Chengli Shen, Victor Zaydfudim, Samantha M. Ruff, Allan Tsung   +6 more
wiley   +1 more source

Saudi Clinical Practice Guideline for the Assessment and Management of Low Back Pain and Sciatica in Adults. [PDF]

J Clin Med
Aldera M, Alturkistany A, Al Rayes H, Rada G, Alsulaimany HH, Alsobayel HI, Alghamdi K, Awwad W, Alyamani OA, Bedaiwi M, Alqahtani Y, Almaghlouth I, Bahlas SM, Alazmi MS, Brunnhuber K, Alhelal F, Alshehri MA.   +16 more
europepmc   +1 more source

Ultrasound‐Guided Nerve Hydrodissection for Sural Nerve Injury: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Sural nerve entrapment is a relatively uncommon cause of lateral ankle and foot pain and sensory disturbance. Conventional management generally lacks direct, targeted intervention at the site of nerve injury. We report a case of a 33‐year‐old male patient who developed sural neuropathy secondary to a right ankle sprain. Diagnosis was confirmed
Mengshan Zhu, Qiang Duan, Liangwen Sun, Fengli Yu, Chunxia Wei, Yumin Wang, Junjie Jian, Bo Wang, Xiaoqun Huang   +8 more
wiley   +1 more source

USP5‐C‐MAF Axis Regulates Autophagy‐Dependent Neuronal Ferroptosis in Spinal Cord Injury Therapeutics

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
SCI induces significant upregulation of USP5 in neurons. The overexpressed USP5 stabilizes c‐MAF protein expression through its deubiquitinase activity, activating autophagy and accelerating the degradation of autophagic ferritin, thereby mediating neuronal ferroptosis. This ultimately leads to impaired functional recovery in SCI mice.
Shiyang Weng, Kai Wu, Yinjun Huang, Lei Cao, Huichao Fu   +4 more
wiley   +1 more source

Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms. [PDF]

Front Mol Neurosci
Li X, Wang X, Song J, Jiang B, Wen Y, Wang Y, Liu B, Zheng X.   +7 more
europepmc   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, Volume 255, Issue 6, Page 548-566, June 2026.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Sciatic Schwannoma in a Patient with Neurofibromatosis Type 1: A Report of a Minimally Invasive Surgical Technique and Review of the Literature. [PDF]

Cureus
Sarpong EO, Rahmanzade R, Mueller A, Egermann H, Sarkadi A.   +4 more
europepmc   +1 more source

Exploring Floristic Diversity and Medicinal Plant Uses in Venda, Limpopo, South Africa

Feddes Repertorium, Volume 137, Issue 2, June 2026.
ABSTRACT Plants have been an important source of medicine for thousands of years. To better understand the current diversity and usage of medicinal plants, floristic studies are essential. This report documents an expedition conducted in the Venda region of Limpopo, South Africa. The study was carried out in Shanzha and surrounding villages, as well as
Gurusamy Manikandan, Iliassou L. Mouafon, David R. Katerere   +2 more
wiley   +1 more source

Druggable Genome-Wide Mendelian Randomization Identifies Distinct Therapeutic Targets for Low Back Pain, Intervertebral Disk Degeneration, and Sciatica. [PDF]

J Pain Res
Sun A, Li Z, Du Y, Liu H, Zhan Q, Liu Z.
europepmc   +1 more source