Veterinary Surgery, EarlyView.Abstract Objective To evaluate the applicability and clinical effectiveness of a modified clamp‐rod internal fixation (M‐CRIF) system compared with conventional locking plate osteosynthesis in the treatment of feline corpus ilium fractures. Study design Prospective, controlled clinical study.
Nahit Saylak +4 more
wiley +1 more source
Sciatica as an atypical initial presentation of multiple myeloma: a case report. [PDF]
AME Case RepJuma AM, Shamtoot Q, Juma MM, Flood J.
europepmc +1 more source
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Experimental Physiology, EarlyView.Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source
Exploring Causal Associations Between Plasma Metabolites and Sciatica: A Two-Sample Mendelian Randomization Analysis. [PDF]
J Pain ResYu S, Wei Q, Luo Y, Wu G.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui +6 more
wiley +1 more source
Efficacy of Multimodal Rehabilitation Protocol with High-Force Machine Spinal Decompression Therapy in Chronic Low Back Pain with Sciatica Due to Lumbar Disc Herniation: A Pre-Post Observational Study. [PDF]
Healthcare (Basel)Nado BBN, Schuster S.
europepmc +1 more source
Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1
The Journal of Physiology, EarlyView.Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang +2 more
wiley +1 more source
Real-World Effectiveness Versus Efficacy in a Study Environment: How Smartphones Help Capture Meaningful Patient Recovery Trajectories - A Commentary on "Physical Performance Continues to Improve After Surgery for Sciatica, Exceeding Recovery Periods of Physical Capacity and Patient-Reported Outcomes: Multicenter Prospective Observational Study". [PDF]
NeurospineStaartjes VE.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Defining glucocorticoid efficacy in Duchenne muscular dystrophy requires assessment across muscle, central nervous system (CNS), cardiovascular and systemic domains. Here, juvenile mdx mice were treated over 6 weeks, comparing daily and weekly dosing of prednisolone and vamorolone.
Gretel S. Major +4 more
wiley +1 more source
Gallic acid exerts therapeutic effects on sciatica by reducing inflammatory responses through the regulation of NOX4-mediated oxidative stress. [PDF]
Front ImmunolChen Z +11 more
europepmc +1 more source