Results 261 to 270 of about 47,052 (316)

Role of Peptides in Skeletal Muscle Wasting: A Scoping Review

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Systemic muscle wasting is a prevalent condition that predicts adverse health outcomes in aging and disease. Despite its clinical relevance, the development of predictive biomarkers and effective pharmacological therapies remains limited. Peptides have recently gained attention for their diverse bioactive functions, positioning them
Petar Naumovski   +9 more
wiley   +1 more source

Pregnancy-Related Hip and Pelvis Musculoskeletal Conditions, Risk Factors, and Prevention. [PDF]

open access: yesCurr Rev Musculoskelet Med
Leung CJ   +4 more
europepmc   +1 more source

STIM1 Reduction Prevents Tubular Aggregate Formation and Compromises Muscle Performance in Ageing Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Ageing is an irreversible process involving the gradual decline of cellular functions in all tissues. In male mice, age‐related loss of muscle force is accompanied by the formation of tubular aggregates, which are honeycomb‐like structures composed of membrane tubules, proteins and Ca2+ deposits. Tubular aggregates are also found in
Laura Pérez‐Guàrdia   +3 more
wiley   +1 more source

Vesicular Rps6 Released by Astrocytes in an Experimental Model of AD Regulates Local Translation and Enhances Synaptic Integrity in Neurones

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
ABSTRACT In neurones, like in any other cell, their function often relies on the fine‐tuning of their protein levels, which is achieved by the balance between protein synthesis and turnover. Defects in protein homeostasis frequently lead to neuronal dysfunction and neurological disorders.
María Gamarra   +7 more
wiley   +1 more source

Intracellular Detection of C. acnes and S. aureus in Non‐Herniated Human Intervertebral Discs: Implications for Catabolic Signaling Pathways

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Cutibacterium acnes and Staphylococcus aureus antigens were detected within non‐herniated intervertebral discs and correlated with catabolic and pyroptotic markers (MMP‐3, GSDMD) and PRRs including NOD2. NP cells exposed to bacterial peptidoglycan showed MAPK/NF‐κB activation and catabolic cytokine release, suggesting that bacterial sensing through a ...
Andrea Nüesch   +5 more
wiley   +1 more source

Comparison between paravertebral injections of ozone and epidural injections of corticosteroids used in the treatment of lumbosacral pain: scoping review. [PDF]

open access: yesMed Gas Res
Arias-Vázquez PI   +5 more
europepmc   +1 more source

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