Segmental zoster paresis of the lower limb with multisegmental lumbosacral plexus involvement: a case report and literature review. [PDF]
Fang F, Liang W, Tang H, Li F.
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Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu +6 more
wiley +1 more source
Degenerative spine surgery: What large-scale outcome registries teach us about indications and timing. [PDF]
Dechambenoit G.
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Neuropathic Pain: From Mechanisms to Therapeutic Interventions
Neuropathic pain arises from peripheral nerve injury, central sensitization, neurotransmitter imbalance, neuroimmune activation, and maladaptive circuit remodeling. Clinical phenotyping and multimodal imaging can identify dominant peripheral and central mechanisms.
Yaling Dai +8 more
wiley +1 more source
The silent burden of sciatica in developing nations: charting a path to reform. [PDF]
Khalid M, Abdullah M.
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Advanced Glycation End Products: From Pathogenesis to Treatment
Therapeutic landscape of AGE‐targeted intervention. Schematic representation of intervention strategies targeting distinct stages of AGE biology. Upstream prevention aims to reduce exposure and formation through low‐AGE cooking, smoking cessation, glycemic control, and metabolic optimization.
Tak‐Ho Lo +7 more
wiley +1 more source
A systematic review and meta-analysis on surgery for lumbar disc herniation: optimal timing of surgery, return to work and outcomes compared with conservative management. [PDF]
Ambaliya S, De Bruyn F, Depreitere B.
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Developing a core outcome set for sciatica: a scoping review of outcome measures. [PDF]
Ridsdale K +6 more
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Causal effect of education on low back pain, intervertebral disc degeneration and sciatica: Mendelian randomization study. [PDF]
Wu Z +7 more
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Saudi Clinical Practice Guideline for the Assessment and Management of Low Back Pain and Sciatica in Adults. [PDF]
Aldera M +16 more
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