Results 231 to 240 of about 25,360 (296)

Acupuncture inhibits astrocytic hyperactivationthe p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1 signaling pathway in cerebral ischemia-reperfusion injury. [PDF]

J Tradit Chin Med
Zifeng Z, Choying WO, Hongling C, Hailiang X, Canghuan Z, Di Z, Peng Q.   +6 more
europepmc   +1 more source

Genetic and Pharmacologic Inhibition of Myostatin Restores Muscle Mass in a Dynamin 2‐Related Centronuclear Myopathy Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Autosomal dominant centronuclear myopathy (ADCNM), most commonly caused by mutations in the dynamin 2 (DNM2) gene, is a rare congenital myopathy characterized by progressive muscle weakness and atrophy. Myostatin, a key negative regulator of skeletal muscle mass, has shown therapeutic potential in several models of neuromuscular ...
Durieux Anne‐Cécile, Arnould David, Velarde Mathias, Allibert Valentine, Paret Chloé, Debelley Quentin, Kizilkilic Esra, Chambon Sidney, Girard Emmanuelle, Collin Louise, Gensel Alexandre, Castells Josiane, Pasternack Aja, Bowen Maximilien, Morel Baptiste, Hourdé Christophe, Laurent Schaeffer, Ritvos Olli, Bitoun Marc, Mounier Rémi, Freyssenet Damien   +20 more
wiley   +1 more source

Agrin‐Enriched Neonatal Spinal Cord‐Derived Extracellular Vesicles Bypass Age Barriers to Organize Spinal Cord Repair

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Spinal cord injury (SCI) poses a formidable challenge in regenerative medicine, with current therapeutic strategies proving largely unsuccessful in achieving functional repair. Notably, paediatric patients and neonatal mice exhibit spontaneous and efficient regeneration after SCI, while the mechanisms remain elusive.
Yongfeng Zhang, Qi Liu, Beibei Yu, Borui Xue, Shijie Yang, Teng Ma, Lingli Guo, Haining Wu, Xue Gao, Shengyou Li, Yujie Yang, Yiming Hao, Ziqing Zhu, Meijia Su, Hongyu Li, Shuanshuan Fan, Jiaqi Wang, Huangtao Chen, Longhui Fu, Anhui Qin, Zhenguo Wang, Shihao Nie, Mingze Qin, Xinxin Bai, Guang Kong, Rui Zhao, Dong Lei, Yue Yu, Junxiong Ma, Shouping Gong, Bing Xia, Jinghui Huang   +31 more
wiley   +1 more source

PCR-confirmed disseminated herpes zoster initially mimicking lumbar radiculopathy in an apparently immunocompetent adult: a case report and literature review. [PDF]

Front Med (Lausanne)
Gao Y.
europepmc   +1 more source

Multiparametric Quantitative MRI of Peripheral Nerves to Differentiate Demyelinating From Axonal Polyneuropathies

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1077-1088, October 2026.
ABSTRACT Background Differentiating demyelinating from axonal polyneuropathies helps for accurate diagnosis and treatment. However, the current clinical tools lack sensitivity to confirm demyelination in peripheral nerves, particularly for proximal nerves.
Jesus E. Fajardo, Vivian B. Truong, Yang Xuan, Sara E. Benitez, Mary L. Vo, Bo Hu, Richard D. Dortch, Jun Li, Yongsheng Chen   +8 more
wiley   +1 more source

Herpes zoster mimicking sciatica: A diagnostic pitfall in immunocompetent middle-aged adult with low back pain. [PDF]

IDCases
Hori D, Sakamoto Y.
europepmc   +1 more source

Myelination and Remyelination in Peripheral Nerve Injury: Mechanisms, Regulation, and Therapeutic Perspectives

MedComm, Volume 7, Issue 10, October 2026.
Peripheral nerve injury triggers axonal degeneration, myelin breakdown, and Schwann cell reprogramming. Remyelination requires reactivation of the SOX10–OCT6–KROX20/EGR2 transcriptional hierarchy, axonal NRG1–ErbB2/3 signaling, metabolic support, and coordinated immune regulation.
Li‐Xin Huang, Tao Sun, Yi‐Bo Zhao, Zhi‐Min Wu, Jun Sun, Ming‐Yang Li, Qing‐Yi Huo, Yun‐Mou Ou, Qing‐Tian Liang, Cong Ling, Bao‐Yu Zhang, Chuan Chen, Ying Guo, Hui Wang   +13 more
wiley   +1 more source

Effectiveness of acupuncture in the treatment of chronic sciatica from herniated disks: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Qu Z, Ju JY, Qin H, Ding YX, Peng LH.
europepmc   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

MedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song, Epiphane K. Silli, Yazhen Xu, Huixia Lv, Ruoxian Song   +4 more
wiley   +1 more source