Results 211 to 220 of about 25,360 (296)

How Do Mindfulness‐Based and Cognitive Behavioral Therapies Help Adults With Opioid‐Treated Chronic Low Back Pain? A Qualitative Study

Pain Practice, Volume 26, Issue 8, November 2026.
ABSTRACT Background Chronic low back pain (CLBP) is common and often refractory to existing treatments, necessitating long‐term opioid therapy, which has substantial risks. Mindfulness‐based (MBT) and cognitive behavioral (CBT) therapies are safe and can be effective for CLBP.
Douwné L. Müller, Eric L. Garland, Robert R. Edwards, Bruce Barrett, Cindy A. Burzinski, Kenneth D. Croes, Robert M. Cradock, Chan Shen, Shilagh A. Mirgain, Janice M. Singles, Aleksandra E. Zgierska   +10 more
wiley   +1 more source

Sciatic and Posterior Femoral Cutaneous Nerve Anomalies and Their Clinical Implications for Sciatica and Piriformis Syndrome: A Cadaveric Case Report. [PDF]

Cureus
Reaux C, Teel SG, Heppner-Lundin NC, Norrod Z, Imam A, Abouzaid KA.   +5 more
europepmc   +1 more source

Ets2 Is an Activity‐Dependent Transcriptional Regulator of a Fast‐Twitch Muscle Program

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Ets2 is a transcription factor rapidly (24 h) upregulated in skeletal muscle by fast 150 Hz, but not slow 20 Hz, stimulation patterns. Ets2 selectively translocates to nuclei of slow soleus muscle when stimulated by fast‐patterned, but not slow‐patterned, activity. Ets2 binds to a consensus DNA sequence in the troponin I fast intronic enhancer (TnIFIRE)
Zaheer A. Rana, Jo C. Bruusgaard, Jens R. Wendland, Ivan Winje, Ingrid M. Egner, Irina Karavanova, Einar Eftestøl, Detlef Vullhorst, Kristian Gundersen, Andres Buonanno   +9 more
wiley   +1 more source

Association Between Isolated Regional Pain and Subsequent Fibromyalgia Documentation: A Retrospective Text-Mined Cohort Study. [PDF]

J Pain Res
Shemesh SZ, Hadari Y, Ungar L.
europepmc   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Potential Role of Mast Cells in Intervertebral Disc Ageing, Herniation Resolution, and Degeneration: Evidence and Lessons Learned from Studies of Mast Cells in Other Connective Tissues. [PDF]

Int J Mol Sci
Hart DA.
europepmc   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, Volume 100, Issue 4, Page 709-736, October 2026.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Methyl eugenol increases neural microcirculation to promote nerve repair by regulating endothelial cell and Schwann cell communication via Ptn/Sdc4. [PDF]

Nat Prod Bioprospect
Zhuang Z, Lin S, Li Y, Xie X, Chen H, Hao Y, Lin L, Zhao G, Zhang D.   +8 more
europepmc   +1 more source

Cannabinoid CB1 Receptor Regulates Spinal Dorsal Horn Synaptic Plasticity in a Mouse Model of Neuropathic Pain through the CB1R/SREBP1/NAMPT/SIRT1 Metabolic Regulatory Framework

Brain and Behavior, Volume 16, Issue 10, October 2026.
Abstract Background Neuropathic pain is sustained by maladaptive synaptic plasticity in the spinal dorsal horn. Increasing evidence suggests that metabolic regulation is closely linked to synaptic function, as lipid metabolism, membrane microdomain organization, NAD+‐dependent signaling, and cellular stress‐response pathways can influence receptor ...
Lu Liu, Chenglong Wu, Hui Xia, Jie Cheng, Liang Zhong, Jiang Wu   +5 more
wiley   +1 more source

Water-Dispersible Palmitoylethanolamide (PEA) Supplementation for Functional Improvement in Adults With Chronic Sciatica-Related Back Pain: A Pilot Clinical Trial. [PDF]

Cureus
Raju HN, Subramanian D, Russo R.
europepmc   +1 more source