Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella +2 more
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Influence of ginger root extract supplementation on the microbiota-gut-brain axis in individuals with sciatica: Study protocol for a double-blind, placebo-controlled randomized trial. [PDF]
Shen CL +11 more
europepmc +1 more source
Klippel–Trénaunay Syndrome With Pelvic/Rectal and Urinary Bladder Involvement: A Rare Case Report
ABSTRACT Concurrent bladder and rectosigmoid vascular malformations in Klippel–Trénaunay syndrome can mimic synchronous pelvic malignancy. Multidisciplinary clinical, radiological, endoscopic, and pathological evaluation is essential to avoid misdiagnosis and to guide appropriate, often conservative, management.
Somaya Al Kiswani +6 more
wiley +1 more source
ABSTRACT A man of 47 had 6 months of left sciatica without root compression on lumbar imaging. Pelvic CT showed isolated left piriformis hypertrophy, 700 versus 450 mm2. Guided betamethasone injection relieved him within 48 h, sustained at 6 months. Asymmetry and response support, but do not prove, sciatic nerve entrapment.
Najoua Ghani
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Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study. [PDF]
Wu L +9 more
europepmc +1 more source
Impaired Motor Function in a Zebrafish Stathmin‐2 Knockout Model
ABSTRACT Stathmin‐2 (STMN2) is a microtubule‐associated protein that plays a role in the stability of microtubules in axons of the nervous system of animals. In this study, we generated a novel zebrafish STMN2 knockout (KO) model. STMN2 is represented by two genes in the zebrafish genome: stmn2a and stmn2b.
Tyler J. N. Gurberg +6 more
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Smoking, Alcohol Use, and Low Back Pain: A Large-Scale Study Identifying a Synergistic Lifestyle Risk. [PDF]
Chang SH, Chen SC, Geng JH.
europepmc +1 more source
After nerve transection in larval zebrafish, proximal and distal Schwann cells have distinct functions at the injury site. Distal repair Schwann cells promote axonal regrowth. Axonal regrowth is normal in mutants with only a few macrophages. ABSTRACT In vertebrate peripheral nerves, damaged axons can regrow after injury, but the outcomes of ...
Daniel E. Lysko +2 more
wiley +1 more source
Traumatic common iliac artery occlusion mimicking acute sciatica: a case report. [PDF]
Chen GY, Wu TC, Kuo JR.
europepmc +1 more source
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto +7 more
wiley +1 more source

