Results 151 to 160 of about 25,967,959 (327)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Learning outcomes in online citizen science communities designed for inquiry [PDF]

open access: hybrid, 2020
Maria Aristeidou   +2 more
openalex   +1 more source

Uranus science planning [PDF]

open access: yes, 1974
Recommendations for a 1979 Mariner Jupiter-Uranus mission are discussed with the possibility of launching the first outer planet atmospheric entry probe.
Moore, J.
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Aspects of Large-Enrollment Online College Science Courses That Exacerbate and Alleviate Student Anxiety

open access: diamond, 2021
Tasneem F. Mohammed   +15 more
openalex   +1 more source

Science of Recording [PDF]

open access: yes, 2008
In what follows I would like to recommend the creation of a new undergraduate course, or, rather, a brand new academic program, with all its MAs, BAs, and PhD programs, dean and faculty, freshmen and freshwomen, applications, debates on newspapers ...
Ferraris, Maurizio
core  

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