Results 51 to 60 of about 28,346,769 (336)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

La nature est un champ de bataille: Rethinking the Mediation between Capital and Nature [PDF]

open access: yesS&F_scienzaefilosofia.it, 2019
Interview to Razmig ...
Keucheyan Razmig
doaj  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Anthropocene and Ecosocialism: a Perspective [PDF]

open access: yesS&F_scienzaefilosofia.it, 2019
Interview to Kohei ...
SAITO, KOHEI
doaj  

Figures of Argument (OSSA 2005 Keynote Address)

open access: yesInformal Logic, 2004
From the seventeenth through the nineteenth centuries, scientists such as Kekule, Mendel, Lavoisier and Harvey argued for insights that depended critically on antithetical expressions and reasoning.
Jeanne Fahnestock
doaj   +1 more source

Cyber-crime Science = Crime Science + Information Security [PDF]

open access: yes, 2010
Cyber-crime Science is an emerging area of study aiming to prevent cyber-crime by combining security protection techniques from Information Security with empirical research methods used in Crime Science.
Hartel, Pieter   +2 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Scientist, Fall 2009 [PDF]

open access: yes, 2009
https://scholarworks.sjsu.edu/scientist/1005/thumbnail ...
San Jose State University, College of Science
core   +1 more source

Pathological Science [PDF]

open access: yes, 2000
I discuss examples of what Dr. Irving Langmuir, a Nobel prize winner in Chemistry, called "the science of things that aren't so." Some of his examples are reviewed and others from High Energy Physics are added. It is hoped that discussing these incidents
Stone, Sheldon
core   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

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