Results 81 to 90 of about 28,346,769 (336)
, 2008 Increasingly, in data-intensive areas of the life sciences, experimental results are being described in algorithmically useful ways with the help of ontologies.
Barry Smith
core +2 more sources
, 2009 We discuss the status of the kilometer-scale neutrino detector IceCube and its low energy upgrade Deep Core and review its scientific potential for particle physics.
+38 more
core +1 more source
Artificial Life, 2003 nationwide data set of losses from 1975 to 1998 was compiled to assess the trends. Temporal patterns of deaths and injuries, monetary damages, and—in some cases—the number of events are systematically examined by year in chapter 5, and the authors ...
Raymond Kurzweil
semanticscholar +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Jurnal Theologia, 2016 : The main purpose of this article (research) is to provide the unity of coherent conceptual frameworks between religion and science on the discourse about the origins of the universe.
Mustofa Umar
doaj +1 more source
Metaphysics of science between metaphysics and science [PDF]
, 2007 The paper argues that metaphysics depends upon science when it comes to claims about the constitution of the real world. That thesis is illustrated by considering the examples of global supervenience, the tenseless vs.
Esfeld, Michael
core +1 more source
Anatomical information science [PDF]
, 2005 The Foundational Model of Anatomy (FMA) is a map of the human body. Like maps of other sorts – including the map-like representations we find in familiar anatomical atlases – it is a representation of a certain portion of spatial reality as it exists at ...
Kumar, Anand +4 more
core +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source