Results 101 to 110 of about 35,847,064 (286)
Cette journée internationale de rencontres est organisée à l’ENS de Lyon à l’occasion du dixième anniversaire de Liens Socio, le portail francophone des sciences sociales. Elle vise à rassembler les compétences des chercheurs et des acteurs nationaux et internationaux les plus innovants en sciences informatiques, en sciences de l’information et en ...
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Global Science Diplomacy For Multilateralism 2.0
This article, published in Science & Diplomacy, a quarterly publication from the AAAS Center for Science Diplomacy, claims that the S&T community not only has the potential to play a significant role in addressing global problems, but they can also be the change agent that strengthens the policy-science nexus at the global level of governance.
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Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
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DIGIS: Digital Geochemistry Infrastructure for GEOROC 2.0
GEOROC is a leading open-access source of geochemical and isotopic datasets and has facilitated thousands of peer-reviewed publications and new avenues of geochemical research. The new Digital Geochemistry Infrastructure (DIGIS) concept of GEOROC 2.0, an
Willbold, Matthias +7 more
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In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
CS-KG 2.0: A Large-scale Knowledge Graph of Computer Science
The rapid evolution of AI and the increased accessibility of scientific articles through open access marks a pivotal moment in research. AI-driven tools are reshaping how scientists explore, interpret, and contribute to the body of scientific knowledge ...
Danilo Dessí +4 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
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Information and communication technology (ICT) advances in research infrastructures are continuously changing the way research and scientific communication are performed. Scientists, funders, and organisations are moving the paradigm of Research Publishing well beyond traditional articles.
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Der Leibniz-Forschungsverbund Science 2.0
Das Wissenschaftsjahr 2014 »Digitale Gesellschaft« wirft insbesondere die Frage auf, in welchem Maße die Digitalisierung der Forschung Wissen prägt und verändert. Die damit einhergehenden Veränderungen werden auch erhebliche Auswirkungen auf Serviceangebote von wissenschaftlichen Bibliotheken haben.
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