Results 111 to 120 of about 35,847,064 (286)
Basic objections to the draft and the adopted Act 2.0 vel the Constitution for science
Studia Historiae Scientiarum, 2018 The article presents essential reservations about the proposal and the adopted Act 2.0 vel Constitution for Science. It focuses on the analysis of two topics: model of university and model of evaluation of journals and books. Our analysis is made in the
Michał Kokowski
doaj
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
POPS 2.0 Use Cases 1-10 v1.0 [PDF]
, 2013 This document defines the Use Cases that will be implemented in the POPS 2.0 system. These Use Cases describe the major functions and activities of the XSEDE allocations process. These activities include: 1) Establish an Allocations Process; 2) Establish
POPS 2.0 Team
core
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Web 2.0 Technologies and Science Education
, 2009 This chapter discusses the potential uses of Web 2.0 technologies in enhancing scientific literacy and the learning of science in the K-12 sector. Web 2.0 offers services and products that could facilitate the learning of science by harnessing the ...
Thiam Seng Koh, Kim Chwee Daniel Tan
core +1 more source
Інформаційні технології і засоби навчанняThe integration of Web 2.0 tools into science education has gained increasing attention because of their potential to enhance student engagement, support interactive learning, and facilitate assessment processes.
Burcu Torun Karakuş +1 more
doaj +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source