Results 31 to 40 of about 1,338,190 (219)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Boom and bust in popular science [PDF]
The obvious thing to say about popular science publishing in the last twenty years is that there has been a lot of it! That is important in itself. But it also means it is hazardous to offer general comment.
Jon Turney
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Scientific publishing: some food for thought (Italian original version) [PDF]
Scientific publishing, here to be considered in a broader sense, as publishing of both specialised scientific journals and science popularisation works addressed to a wider audience, has been sailing for some years on troubled waters.
Vittorio Bo
doaj
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Scientific publishing: some food for thought [PDF]
Scientific publishing, here to be considered in a broader sense, as publishing of both specialised scientific journals and science popularisation works addressed to a wider audience, has been sailing for some years on troubled waters.
Vittorio Bo
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Jaap Willems and Winfried Goepfert (eds.), Science and the power of TV, VU University press and Da Vinci Institute, Amsterdam, 2006 [PDF]
We live in a period where new media develops at amazing speed: the case of Youtube, becoming in few months one of the most visited website in the world, or the incredibly fast diffusion of audio and video podcasting, or the acquired relevance and ...
Matteo Merzagora
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Why should we care about science books? [PDF]
Why should we care about science books? After all, we live in a "new media" world where students, researchers, and the public use the World Wide Web for all their information needs.
Bruce V. Lewenstein
doaj

