Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Science on the net: an analysis of the websites of the European public research institutions (Italian original version) [PDF]
This article introduces a study on the websites of several European public research institutions that aims at identifying the science communication model chosen and implemented online with the purpose of reaching different target publics.
Laura Massoli
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Examining science and media literacy health communication messages to reduce intentions to use cannabis while pregnant. [PDF]
Willoughby JF +9 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Grid computing and e-science: a view from inside [PDF]
My intention is to analyze how, where and if grid computing technology is truly enabling a new way of doing science (so-called ‘e-science’). I will base my views on the experiences accumulated thus far in a number of scientific communities, which we have
Stefano Cozzini
doaj
Guidelines, top-notch science & social media-Jump on the bandwagon. [PDF]
Pawlak KM, Wauters L.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Public domain, copyright licenses and the freedom to integrate science [PDF]
From the life sciences to the physical sciences, chemistry to archaeology, the last 25 years have brought an unprecedented shift in the way research happens day to day, and the average scientist is now simply awash in data.
John Wilbanks
doaj
Trust in Science, Perceived Media Exaggeration About COVID-19, and Social Distancing Behavior. [PDF]
Neureiter A +3 more
europepmc +1 more source

