Results 71 to 80 of about 1,338,190 (219)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
JCOM: Journal of Science Communication, 2008 Internet and the new media have been dramatically affecting the communication scenario. They are changing the role played by traditional media in the information processes, are creating new public spaces for dialogue and participation, and are triggering
Ilenia Picardi, Simona Regina
doaj
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Quality characteristics in IoT systems: learnings from an industry multi case study
Discover Internet of ThingsThe Internet of Things (IoT) has transformed our daily life by enabling devices and objects to collect data, communicate, and collaborate to provision novel types of services.
Fahed Alkhabbas +3 more
doaj +1 more source
Science via podcast (Italian original version) [PDF]
JCOM: Journal of Science Communication, 2008 Internet and the new media have been dramatically affecting the communication scenario. They are changing the role played by traditional media in the information processes, are creating new public spaces for dialogue and participation, and are triggering
Ilenia Picardi, Simona Regina
doaj
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
To blog or not to blog, not a real choice there... [PDF]
JCOM: Journal of Science Communication, 2008 Science blogging is a very useful system for scientists to improve their work, to keep in touch with other colleagues, to access unfamiliar science developed in other fields, to open new collaborations, to gain visibility, to discuss with the public.
Elisabetta Tola
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The growth of social media in science: Social media has evolved from a mere communication channel to an integral tool for discussion and research collaboration. [PDF]
EMBO Rep, 2020 Hunter P.
europepmc +1 more source