Results 71 to 80 of about 199,533 (304)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gene Technology, Biological Weapons, and the Security of Science

open access: yesSecurity Studies, 2009
This article addresses the security challenge posed by laboratory research involving genetic modification of microorganisms that could be applied for both benign and malevolent purposes. The authors propose that, for biological arms control purposes, a global governance culture is required to manage the security risks inherent in such research while ...
Enemark, Christian, Ramshaw, Ian
openaire   +2 more sources

Marsh Seeks to Capitalize on Bio-Threat Technology [PDF]

open access: yes, 2012
Center for Homeland Defense and Security, PRESS RELEASESCaptain Bryon Marsh had a vision to capitalize on emerging bio-threat detection technology when he enrolled at the Naval Postgraduate School Center for Homeland Defense and Security.
Center for Homeland Defense and Security
core  

Advanced Security for Virtual Organizations: The Pros and Cons of Centralized vs Decentralized Security Models [PDF]

open access: yes, 2008
Grids allow for collaborative e-Research to be undertaken, often across institutional and national boundaries. Typically this is through the establishment of virtual organizations (VOs) where policies on access and usage of resources across partner sites
Chadwick, D. W.   +21 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Institute for Security Technology Studies [PDF]

open access: yes
The Institute for Security Technology Studies (ISTS) at Dartmouth College "is dedicated to pursuing research that addresses critical national needs for security technology and policy in cyber and emergency response environments." Its ...

core  

User oriented access to secure biomedical resources through the grid [PDF]

open access: yes, 2006
The life science domain is typified by heterogeneous data sets that are evolving at an exponential rate. Numerous post-genomic databases and areas of post-genomic life science research have been established and are being actively explored. Whilst many of
Watt, J   +9 more
core  

S&T Artificial Intelligence & Machine Learning Strategic Plan [PDF]

open access: yes, 2021
This report presents goals that will enable the Science and Technology Directorate to conduct artificial intelligence and machine learning research, development, test, and evaluation activities to support DHS mission ...
United States. Department of Homeland Security. Science and Technology Directorate   +1 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

New Book Announcement: Network Science: Theory and Application [PDF]

open access: yes, 2009
Center for Homeland Defense and Security, PRESS RELEASESNEW BOOK ANNOUNCEMENT Electrical & Electronics Engineering / Communication Technology / Networks Network Science: Theory and Applications Ted Lewis, CHDS Executive Director Hardcover; 524 pages ...
Center for Homeland Defense and Security
core  

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