Results 81 to 90 of about 199,533 (304)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Supporting security-oriented, collaborative nanoCMOS electronics research [PDF]
Grid technologies support collaborative e-Research typified by multiple institutions and resources seamlessly shared to tackle common research problems.
Sinnott, RO +17 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Cyber Security Longitudinal Survey: Wave 3, 2024 [PDF]
copyright UK Data Service and data collection copyright owner.The Cyber Security Longitudinal Survey (CSLS) helps us better understand cyber security policies and processes within medium and large businesses and high-income charities.
Department for Science, Innovation and Technology
core
New cryptographic protocols With side-channel attack security [PDF]
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012."June 2012." Cataloged from PDF version of thesis.Includes bibliographical references (p.
Miller, Rachel A., S.M. (Rachel Ann). Massachusetts Institute of Technology
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
ReMamba: a hybrid CNN-Mamba aggregation network for visible-infrared person re-identification
Visible-Infrared Person Re-identification (VI-ReID) has been consistently challenged by the significant intra-class variations and cross-modality differences between different cameras.
Haokun Geng +6 more
doaj +1 more source
Policy, Practice, and the Search for Alpha [PDF]
This article appeared in Homeland Security Affairs (March 2011), Supplement no.3If there were a scale to measure the level of abstraction associated with science, technology, strategy, and policy, we could think of science and technology at one end and ...
Josefek, Robert
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

